Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.35 |
| ▸ | CCKAR | P32238 | 2/20 | 0.35 |
| ▸ | CCKBR | P32239 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142438 | 0.89 | ITGB1 (0.42) | ITGB1ITGAVITGA4GHSRMAPT | |
| SCHEMBL4624866 | 0.86 | ITGB1 (0.52) | SMN1; SMN2ITGB1ITGAVMEN1KMT2A | |
| SCHEMBL4626488 | 0.81 | ITGB1 (0.64) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL4624055 | 0.80 | ITGA4 (0.51) | SMN1; SMN2ITGB1MEN1KMT2AITGA4 | |
| SCHEMBL3319927 | 0.80 | ITGB1 (0.62) | ITGB1ITGAVMEN1KMT2AITGA4 | |
| SCHEMBL4624998 | 0.77 | ITGB1 (0.54) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL4624246 | 0.75 | ITGB1 (0.64) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL1028110 | 0.75 | ITGB1 (0.55) | ITGB1ITGAVMEN1KMT2AITGA4 | |
| SCHEMBL4625005 | 0.73 | ITGB1 (0.40) | SMN1; SMN2ITGB1ITGAVMEN1KMT2A | |
| SCHEMBL4627182 | 0.72 | ITGB1 (0.54) | ITGB1ITGAVITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501801-B1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF VLA-4 DEPENDENT DISEASES | UCB PHARMA SA (BE) | 2008-01-23 | — | — | EP | disclosed |