Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.57 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.57 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11483097 | 0.98 | PTGS2 (0.59) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL59197 | 0.88 | PTGS2 (0.74) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL11724969 | 0.85 | AKR1C3 (0.63) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL27536644 | 0.84 | ACACB (0.46) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL6551674 | 0.81 | PTGS2 (0.65) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL917093 | 0.81 | PTGS2 (0.87) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL4651605 | 0.81 | PTGS2 (0.65) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL459261 | 0.80 | EPHX1 (0.58) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL29318759 | 0.80 | ACACB (0.43) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL10333915 | 0.79 | PTGS1 (0.59) | PTGS2PTGS1AKR1C3AKR1C2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5140028-A | — | — | None | — | — | JP | disclosed |
| JP-5140028-A | — | — | None | — | — | JP | disclosed |
| CN-118955244-A | Method for preparing primary alcohol by homogeneously catalyzing and reducing carboxylic acid derivative by using N-heterocyclic carbene copper complex | 延安大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-118076367-A | GLP-1 receptor agonists with improved pharmacological and drug delivery properties | 达比克斯有限责任公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-114292226-B | Compound with hydroxamic acid structure and preparation method and application thereof | 沈阳药科大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-112479921-B | Compound with PPAR delta agonist activity, pharmaceutical composition and medical application | 中国药科大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-114292226-A | Compound with hydroxamic acid structure and preparation method and application thereof | 沈阳药科大学 | 2022-04-08 | — | — | CN | disclosed |
| CN-109970542-B | Application of quebrachitol in copper-catalyzed aryl halide hydrolysis reaction | 沈阳药科大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-112479921-A | Compound with PPAR delta agonist activity, pharmaceutical composition and medical application | 中国药科大学 | 2021-03-12 | — | — | CN | disclosed |
| CN-111704912-A | Novel preparation method of 3-alkenyl benzyne liquid crystal compound | 烟台丰蓬液晶材料有限公司 | 2020-09-25 | — | — | CN | disclosed |
| US-6359135-B1 | Compounds having activity as inhibitors of cytochrome P450RAI | ALLERGAN SALES, INC. | 2002-03-19 | — | — | US | disclosed |
| WO-2002018361-A2 | COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF CYTOCHROME P450RAI | ALLERGAN, INC. (US) | 2002-03-07 | — | — | WO | disclosed |
| US-6313107-B1 | ADMINISTERING TO MAMMAL TO TREAT DISEASES RESPONSIVE TO TREATMENT BY RETINOIDS | ALLERGAN SALES, INC. | 2001-11-06 | — | — | US | disclosed |
| US-6303785-B1 | SUBSTITUTED N-CYCLOPROPYLTETRAHYDROISOQUINOLINES | ALLERGAN SALES, INC. | 2001-10-16 | — | — | US | disclosed |
| US-6291677-B1 | FOR TREATING SKIN-RELATED DISEASES, INCLUDING, ACTINIC KERATOSES, ARSENIC KERATOSES, INFLAMMATORY AND NON-INFLAMMATORY ACNE, PSORIASIS, ICHTHYOSES AND KERATINIZATION AND HYPERPROLIFERATIVE DISORDERS OF SKIN | ALLERGAN SALES, INC. | 2001-09-18 | — | — | US | disclosed |
| US-6252090-B1 | Compounds having activity as inhibitors of cytochrome P450RAI | ALLERGAN SALES, INC. | 2001-06-26 | — | — | US | disclosed |
| JP-H05140028-A | PRODUCTION OF 2-(4-IODOPHENYL)-PROPIONIC ACID AND ITS ESTER | NAGASE SANGYO KK | 1993-06-08 | — | — | JP | disclosed |
| JP-H05140028-A | PRODUCTION OF 2-(4-IODOPHENYL)-PROPIONIC ACID AND ITS ESTER | NAGASE SANGYO KK | 1993-06-08 | — | — | JP | disclosed |
| US-4252719-A | REMOVAL OF A TERTIARY HYDROGEN FROM A 5-A-STEROID BY CHLORINATING THE STEROID BEING FIRST ESTERIFIED BY AN IODOARYL-CONTAINING ESTERIFICATION AGENT | RESEARCH CORPORATION (US) | 1981-02-24 | — | — | US | disclosed |
| US-4230719-A | Novel 2-[4-(3-methyl-2-thienyl)phenyl]propionic acid and pharmaceutically acceptable salt thereof and method for treating symptoms of inflammation and pain | TOYAMA CHEMICAL CO., LTD. (JP) | 1980-10-28 | — | — | US | disclosed |