SCHEMBL917093

SCHEMBL917093

CC(C(=O)O)c1ccc(-c2ccc(C(C)C(=O)O)cc2)cc1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 13/20 0.87
PTGS1 P23219 4/20 0.61
LMNA P02545 2/20 0.61
CYP2C9 P11712 2/20 0.61
AKR1C3 P42330 2/20 0.61
CXCR1 P25024 2/20 0.61
CXCR2 P25025 2/20 0.61
ALB P02768 1/20 0.61
ESR1 P03372 1/20 0.61
ALOX5 P09917 1/20 0.61
RARB P10826 1/20 0.61
ADRB3 P13945 1/20 0.61
NFKB1 P19838 1/20 0.61
HTR2A P28223 1/20 0.61
NR1I3 Q14994 1/20 0.61
SLC22A6 Q4U2R8 1/20 0.61
CXCL8 P10145 1/20 0.61
TSHR P16473 1/20 0.61
AKR1C2 P52895 1/20 0.61
BLM P54132 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1211557 0.93 PTGS2 (1.00) PTGS2PTGS1LMNACYP2C9AKR1C3
SCHEMBL7826539 0.93 PTGS2 (1.00) PTGS2PTGS1LMNACYP2C9AKR1C3
SCHEMBL59197 0.92 PTGS2 (0.74) PTGS2PTGS1LMNACYP2C9AKR1C3
SCHEMBL1678786 0.91 PTGS2 (0.74) PTGS2PTGS1LMNACYP2C9AKR1C3
Hydrochloric Acid SCHEMBL5753890 0.91 PTGS2 (0.96) PTGS2PTGS1LMNACYP2C9AKR1C3
SCHEMBL9592228 0.89 PTGS2 (0.71) PTGS2PTGS1LMNACYP2C9AKR1C3
SCHEMBL11884258 0.89 PTGS2 (0.71) PTGS2PTGS1LMNACYP2C9AKR1C3
SCHEMBL28874185 0.88 PTGS2 (0.69) PTGS2PTGS1LMNACYP2C9AKR1C3
SCHEMBL1678493 0.86 PTGS2 (0.67) PTGS2PTGS1AKR1C3ALOX5SLC22A6
SCHEMBL6551674 0.85 PTGS2 (0.65) PTGS2PTGS1LMNACYP2C9AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8437067-B2 Electrochemical display element KONICA MINOLTA HOLDINGS, INC. (JP) 2013-05-07 US disclosed
US-20110019265-A1 DISPLAY ELEMENT AND METHOD OF FORMING POROUS LAYER IN DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-27 US disclosed
US-20110013261-A1 ELECTROCHEMICAL DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-20 US disclosed