SCHEMBL4538261

SCHEMBL4538261

C1=CC2(CC3CCC2C3)Oc2c1ccc1ccccc21

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 3/20 0.34
HTR2A P28223 2/20 0.34
ALOX5AP P20292 2/20 0.32
NFKB1 P19838 2/20 0.30
NFKB2 Q00653 2/20 0.30
RELA Q04206 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29756154 1.00 HTR2C (0.34) HTR2CHTR2AALOX5APNFKB1NFKB2
SCHEMBL4609204 0.80 PNMT (0.32)
SCHEMBL9035829 0.75 HTR2C (0.34) HTR2CHTR2ANFKB1NFKB2RELA
SCHEMBL4625971 0.74 HTR2C (0.36) HTR2CHTR2A
SCHEMBL26289831 0.73 KDM4E (0.35)
SCHEMBL8681014 0.72 ALDH1A1 (0.39) HTR2CHTR2A
SCHEMBL14631751 0.71 SLC6A2 (0.31) HTR2CHTR2A
SCHEMBL9035491 0.70 SLC6A2 (0.33) HTR2CHTR2A
SCHEMBL15196167 0.69 ALDH1A1 (0.37)
SCHEMBL9917550 0.69 HSD17B10 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5140548-A None JP disclosed
EP-3521907-B1 PHOTOCHROMIC LENS AND POLYMERIZABLE COMPOSITION MITSUI CHEMICALS INC (JP) 2024-12-04 EP disclosed
EP-3438147-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL OBTAINED FROM COMPOSITION, AND PLASTIC LENS MITSUI CHEMICALS INC (JP) 2023-06-21 EP disclosed
US-11472943-B2 Polymerizable composition for optical material, optical material, and application thereof MITSUI CHEMICALS, INC. (JP) 2022-10-18 US disclosed
CN-110831992-B Polymerizable composition for optical material and molded article 三井化学株式会社 2022-08-23 CN disclosed
US-11414515-B2 Polymerizable composition for optical material and optical material and plastic lens obtainable from same composition MITSUI CHEMICALS, INC. (JP) 2022-08-16 US disclosed
CN-109689698-B Polymerizable composition for optical material and molded article 三井化学株式会社 2022-05-31 CN disclosed
EP-3521322-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, AND MOLDED BODY MITSUI CHEMICALS INC (JP) 2022-03-09 EP disclosed
US-11248077-B2 Polymerizable composition for optical material and molded product MITSUI CHEMICALS, INC. (JP) 2022-02-15 US disclosed
US-20210054126-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL AND MOLDED PRODUCT MITSUI CHEMICALS, INC. (JP) 2021-02-25 US disclosed
EP-0773273-A1 PROCESS FOR THE PRODUCTION OF PHOTOCHROMIC PRODUCT OF CURING TOKUYAMA CORPORATION (JP) 1997-05-14 EP disclosed
US-5621017-A PHOTOCHROMIC COMPOSITION INCLUDING RADICAL POLYMERIZABLE MONOMER, CHROMENE AND/OR SPIROOXAZINE BASED PHOTOCHROMIC COMPOUND, PHOTOPOLYMERIZATION INITIATOR TOKUYAMA CORPORATION (JP) 1997-04-15 US disclosed
EP-0696582-A1 Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides TOKUYAMA CORPORATION (JP) 1996-02-14 EP disclosed
EP-0681018-A2 Photochromic composition and method of producing photochromic cured product TOKUYAMA CORPORATION (JP) 1995-11-08 EP disclosed
US-5462698-A Lenses TOKUYAMA CORPORATION (JP) 1995-10-31 US disclosed
US-5395566-A Addition polymerizable composition, epoxy monomer, imide or anhydride containing fused ring photochromic compound, lenses TOKUYAMA CORPORATION (JP) 1995-03-07 US disclosed
EP-0629626-A2 Cyclopropyl-substituted spiro-photochromic compounds TOKUYAMA CORPORATION (JP) 1994-12-21 EP disclosed
EP-0619358-A1 Photochromic composition TOKUYAMA CORPORATION (JP) 1994-10-12 EP disclosed
EP-0559439-A2 Photochromic composition TOKUYAMA CORPORATION (JP) 1993-09-08 EP disclosed
JP-H05140548-A PHOTOCHROMIC MOLDING TOKUYAMA SODA CO LTD 1993-06-08 JP disclosed