Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27724385 | 0.79 | CCR5 (0.53) | MMP2MMP9HRH3 | |
| SCHEMBL31709003 | 0.75 | CHRM3 (0.55) | SIGMAR1KCNH2 | |
| SCHEMBL31708843 | 0.75 | CHRM3 (0.55) | SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL1449121 | 0.74 | SMN1; SMN2 (0.59) | — | |
| SCHEMBL31709258 | 0.73 | CHRM3 (0.56) | SIGMAR1KCNH2 | |
| SCHEMBL11246294 | 0.72 | ADRB1 (0.45) | SIGMAR1 | |
| SCHEMBL8176746 | 0.72 | SIGMAR1 (0.62) | SIGMAR1CCR3 | |
| SCHEMBL7405795 | 0.71 | SIGMAR1 (0.72) | HRH3SIGMAR1KCNH2CCR3 | |
| SCHEMBL4624806 | 0.71 | SLC6A2 (0.52) | MMP2MMP9 | |
| SCHEMBL11574478 | 0.70 | KCNA3 (0.58) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687288-B1 | SUBSTITUTED ARYL CYCLOALKANOL DERIVATIVES AND METHODS OF THEIR USE | WYETH CORP (US) | 2008-01-16 | — | — | EP | disclosed |