Octane

Octane

SCHEMBL4626385

C1CCOC1.CCCCCCCC

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
ALDH1A1 P00352 4/20 0.50
THRB P10828 1/20 0.50
LMNA P02545 3/20 0.44
EPHX1 P07099 1/20 0.42
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
DNM1 Q05193 4/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SLC22A1 O15245 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptane SCHEMBL538473 1.00 TSHR (0.50) TSHRALDH1A1THRBLMNAEPHX1
Nonane SCHEMBL8960871 1.00 TSHR (0.50) TSHRALDH1A1THRBLMNAEPHX1
Heptane SCHEMBL25303431 0.97 ALDH1A1 (0.47) TSHRALDH1A1THRBLMNAEPHX1
Heptane SCHEMBL4434566 0.97 ALDH1A1 (0.47) TSHRALDH1A1THRBLMNAEPHX1
Hexane SCHEMBL5237862 0.97 ALDH1A1 (0.53) TSHRALDH1A1THRBLMNAEPHX1
Hexane SCHEMBL22134480 0.97 ALDH1A1 (0.53) TSHRALDH1A1THRBLMNAEPHX1
Hexane SCHEMBL224276 0.97 ALDH1A1 (0.53) TSHRALDH1A1THRBLMNAEPHX1
Hexane SCHEMBL14895621 0.97 ALDH1A1 (0.53) TSHRALDH1A1THRBLMNAEPHX1
Nonane SCHEMBL9452411 0.94 TSHR (0.44) TSHRALDH1A1THRBLMNACES2
Heptane SCHEMBL21580605 0.94 TSHR (0.44) TSHRALDH1A1THRBLMNACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304320-B1 Preparation of esters of carboxylic acids EASTMAN CHEM CO (US) 2008-05-28 EP disclosed
CN-1297532-C Preparation of carboxylic acid ester EASTMAN CHEM CO (US) 2007-01-31 CN disclosed
EP-1304320-A2 Preparation of esters of carboxylic acids EASTMAN CHEMICAL COMPANY (US) 2003-04-23 EP disclosed
CN-1412172-A Preparation of carboxylic acid ester EASTMAN CHEM CO (US) 2003-04-23 CN disclosed
US-6518454-B1 A process wherein a solution of a carboxylic acid in a first solvent and an alcohol are fed to a simulated moving bed reactor (SMBR) containing a solid(s) to produce a first stream comprising a solution of an ester of the carboxylic acid with EASTMAN CHEMICAL COMPANY 2003-02-11 US disclosed
US-4585591-A 17β-ethynylsteroids and process for preparing same MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1986-04-29 US disclosed
EP-0071178-B1 ACYLOXYSTEROIDS AND PROCESS FOR PRODUCING SAME MITSUBISHI KASEI CORPORATION (JP) 1985-10-16 EP disclosed
EP-0053845-B1 17-BETA-ETHYNYLSTEROIDS AND PROCESS FOR PREPARING SAME MITSUBISHI KASEI CORPORATION (JP) 1985-04-10 EP disclosed
US-4440689-A Acyloxysteroids and process for producing same MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1984-04-03 US disclosed
EP-0071178-A1 Acyloxysteroids and process for producing same MITSUBISHI KASEI CORPORATION (JP) 1983-02-09 EP disclosed
EP-0053845-A1 17-Beta-ethynylsteroids and process for preparing same MITSUBISHI KASEI CORPORATION (JP) 1982-06-16 EP disclosed