Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL22134480 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TSHRLMNATHRBEPHX1 | |
| Hexane SCHEMBL14895621 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TSHRLMNATHRBEPHX1 | |
| Hexane SCHEMBL5237862 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TSHRLMNATHRBEPHX1 | |
| Heptane SCHEMBL538473 | 0.97 | TSHR (0.50) | ALDH1A1TSHRLMNATHRBEPHX1 | |
| Hexane SCHEMBL28093142 | 0.97 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNATHRBEPHX1 | |
| Nonane SCHEMBL8960871 | 0.97 | TSHR (0.50) | ALDH1A1TSHRLMNATHRBEPHX1 | |
| Octane SCHEMBL4626385 | 0.97 | TSHR (0.50) | ALDH1A1TSHRLMNATHRBEPHX1 | |
| Hexane SCHEMBL7204589 | 0.97 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNATHRBEPHX1 | |
| Hexane SCHEMBL5304985 | 0.97 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNATHRBEPHX1 | |
| Hexane SCHEMBL11154641 | 0.97 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNATHRBEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307522-A | Preparation method of oxatinib mesylate | 河北泽冀科技有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-118090939-A | Method for measuring migration quantity of ultraviolet absorber in food contact material and product | 宁波检验检疫科学技术研究院(宁波国检贸易便利化服务中心) | 2024-05-28 | — | — | CN | claimed |
| CN-117903401-A | Polyfluoro siloxane polyurethane, preparation method and application thereof, and marine protective coating | 青岛理工大学 | 2024-04-19 | — | — | CN | claimed |
| CN-116041294-A | Method for preparing hexahydrophthalide by phthalic anhydride or phthalic acid | 中国科学院兰州化学物理研究所 | 2023-05-02 | — | — | CN | claimed |
| CN-112098543-B | Method for measuring contents of various perfume compounds in sole material | 深圳天祥质量技术服务有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-114436977-A | Favipiravir multi-component medicine and preparation method and application thereof | 山东大学 | 2022-05-06 | — | — | CN | claimed |
| CN-112546234-A | Favipiravir medicinal conjugate and application thereof in preparation of antiviral medicinal preparation | 山东大学 | 2021-03-26 | — | — | CN | claimed |
| CN-112098543-A | Method for measuring contents of various perfume compounds in sole material | 深圳天祥质量技术服务有限公司 | 2020-12-18 | — | — | CN | claimed |
| CN-104817583-B | Carbon bridging bisamide base ytterbium and its preparation and the application in catalysis aldehyde and amine amide are combined to react | 苏州大学 | 2019-03-12 | — | — | CN | claimed |
| CN-108794342-A | Ammonium carboxylate salt compound, its crystal form, amorphous substance and preparation method thereof | 武汉朗来科技发展有限公司 | 2018-11-13 | — | — | CN | claimed |
| US-20110295042-A1 | METHOD FOR PREPARING PROPARGYLIC ALCOHOL CATALYZED BY 2-MORPHOLINOISOBORNANE-10-THIOL | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-01 | — | — | US | claimed |
| US-7485663-B2 | Carvedilol | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-02-03 | — | — | US | claimed |
| CN-101130522-A | Novel method for synthesizing fungicide tebuconazole | SHANGHAI SHENGNONG PESTICIDE C (CN) | 2008-02-27 | — | — | CN | claimed |
| US-20040225132-A1 | Carvedilol | HILDESHEIM JEAN (IL) | 2004-11-11 | — | — | US | claimed |
| US-6552209-B1 | Such as reacting tantalum pentachloride with tertbutylamine and pyridine; stripping solvent and extracting into tetra-hydrofuran; adding extract to fresh in situ prepared lithium diethylamine solution; high yield and purity | AIR PRODUCTS AND CHEMICALS, INC. | 2003-04-22 | — | — | US | claimed |
| US-20020143045-A1 | Carvedilol | TEVA PHARMACEUTICALS USA, INC. | 2002-10-03 | — | — | US | claimed |
| EP-0643689-B1 | IMPROVED PROCESS FOR THE SYNTHESIS OF (5R)-1,1-DIMETHYLETHYL 6-CYANO-5-HYDROXY-3-OXO-HEXANOATE | WARNER LAMBERT CO (US) | 1998-12-30 | — | — | EP | claimed |
| EP-0643689-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF (5R)-1,1-DIMETHYLETHYL 6-CYANO-5-HYDROXY-3-OXO-HEXANOATE | WARNER-LAMBERT COMPANY (US) | 1995-03-22 | — | — | EP | claimed |
| WO-1993007115-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF (5R)-1,1-DIMETHYLETHYL 6-CYANO-5-HYDROXY-3-OXO-HEXANOATE | WARNER-LAMBERT COMPANY (US) | 1993-04-15 | — | — | WO | claimed |
| US-5155251-A | Process for the synthesis of (5R)-1,1-dimethylethyl-6-cyano-5-hydroxy-3-oxo-hexanoate | WARNER-LAMBERT COMPANY (US) | 1992-10-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040225132-A1 | Carvedilol | REN, ADRB1, ADRB2 | ALDH1A1 1694/4885TSHR 3165/4885LMNA 559/4885 |
| US-20020143045-A1 | Carvedilol | REN, ADRB1, ADRB2 | ALDH1A1 1694/4885TSHR 3165/4885LMNA 559/4885 |
| US-20110295042-A1 | METHOD FOR PREPARING PROPARGYLIC ALCOHOL CATALYZED BY 2-MORPHOLINOISOBORNANE-10-THIOL | GRHPR, ADH1C, ADH5 | ALDH1A1 99/4885TSHR 290/4885LMNA 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.