Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptane SCHEMBL538473 | 1.00 | TSHR (0.50) | TSHRALDH1A1THRBLMNAEPHX1 | |
| Octane SCHEMBL4626385 | 1.00 | TSHR (0.50) | TSHRALDH1A1THRBLMNAEPHX1 | |
| Heptane SCHEMBL25303431 | 0.97 | ALDH1A1 (0.47) | TSHRALDH1A1THRBLMNAEPHX1 | |
| Heptane SCHEMBL4434566 | 0.97 | ALDH1A1 (0.47) | TSHRALDH1A1THRBLMNAEPHX1 | |
| Hexane SCHEMBL5237862 | 0.97 | ALDH1A1 (0.53) | TSHRALDH1A1THRBLMNAEPHX1 | |
| Hexane SCHEMBL22134480 | 0.97 | ALDH1A1 (0.53) | TSHRALDH1A1THRBLMNAEPHX1 | |
| Hexane SCHEMBL224276 | 0.97 | ALDH1A1 (0.53) | TSHRALDH1A1THRBLMNAEPHX1 | |
| Hexane SCHEMBL14895621 | 0.97 | ALDH1A1 (0.53) | TSHRALDH1A1THRBLMNAEPHX1 | |
| Nonane SCHEMBL9452411 | 0.94 | TSHR (0.44) | TSHRALDH1A1THRBLMNACES2 | |
| Heptane SCHEMBL21580605 | 0.94 | TSHR (0.44) | TSHRALDH1A1THRBLMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348472-A | Macrocyclic compounds | 旭化成制药株式会社 | 2023-06-27 | — | — | CN | disclosed |
| CN-113234079-B | Nucleoside analogs as PRMT5 inhibitors | 上海湃隆生物科技有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113234079-A | Nucleoside analogs as PRMT5 inhibitors | 上海湃隆生物科技有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-108947863-B | Preparation method of nucesin and intermediate thereof | 上海博志研新药物技术有限公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-110268539-A | Organic electronic material, organic electronic element and organic electroluminescent device | 日立化成株式会社 | 2019-09-20 | — | — | CN | disclosed |
| CN-109535155-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-103958508-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-104910148-B | Aminotriazole(ATA) and pyridine and its as kinase inhibitor purposes | 西格诺药品有限公司 | 2017-06-27 | — | — | CN | disclosed |
| CN-103958508-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBVIE INC | 2014-07-30 | — | — | CN | disclosed |
| CN-1930145-B | Cycloalkanopyridine derivative | MSD CO LTD | 2011-06-15 | — | — | CN | disclosed |
| CN-101605795-A | Tricyclic compounds and pharmaceutical uses thereof | TAKEDA PHARMACEUTICAL (JP) | 2009-12-16 | — | — | CN | disclosed |
| CN-1930145-A | Cycloalkanopyridine derivative | BANYU PHARMA CO LTD (JP) | 2007-03-14 | — | — | CN | disclosed |
| US-5510366-A | INOTROPIC, ANTIARRHYMTHMIA AGENTS, VASODILATORS | KOWA CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0274912-B1 | PROCESS FOR PREPARING POLYALCOHOL COPOLYMERS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1993-02-24 | — | — | EP | disclosed |