Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GOT1 | P17174 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19321566 | 0.84 | MAPT (0.63) | TDP1KDM4EMAPTL3MBTL1NPSR1 | |
| SCHEMBL438327 | 0.80 | PIK3CG (0.46) | KDM4EMAPTALDH1A1POLBRAB9A | |
| Salicyladehyde SCHEMBL2801260 | 0.80 | TRIM24 (0.50) | TDP1KDM4EMAPTRXFP1L3MBTL1 | |
| SCHEMBL14067142 | 0.78 | TDP1 (0.58) | TDP1KDM4EMAPTRXFP1L3MBTL1 | |
| SCHEMBL10846397 | 0.78 | PGK1 (0.44) | GOT1 | |
| SCHEMBL23234459 | 0.77 | HTT (0.43) | KDM4ERXFP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10846446 | 0.77 | RXFP1 (0.45) | TDP1KDM4EMAPTRXFP1L3MBTL1 | |
| SCHEMBL437073 | 0.77 | NQO2 (0.48) | TDP1KDM4EMAPTRXFP1L3MBTL1 | |
| SCHEMBL14828909 | 0.77 | GOT1 (0.40) | TDP1KDM4EMAPTRXFP1L3MBTL1 | |
| SCHEMBL29451077 | 0.75 | TDP1 (1.00) | TDP1KDM4EMAPTRXFP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102250022-B | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2013-10-16 | — | — | CN | claimed |
| CN-102250022-A | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2011-11-23 | — | — | CN | claimed |
| EP-3325486-B1 | POLYNITROGEN COMPOUNDS AND USES THEREOF AS FLUORESCENT CHROMOPHORES | UNIV ORLEANS (FR) | 2023-05-24 | — | — | EP | disclosed |
| EP-3325486-B1 | POLYNITROGEN COMPOUNDS AND USES THEREOF AS FLUORESCENT CHROMOPHORES | UNIV ORLEANS (FR) | 2023-05-24 | — | — | EP | disclosed |
| US-11028090-B2 | [1,2,4]Triazolo[4,3-a]quinoxaline derivative, method for preparing same, and pharmaceutical composition for preventing or treating BET protein-related diseases, containing same as active ingredient | DONG WHA PHARM. CO., LTD. (KR) | 2021-06-08 | — | — | US | disclosed |
| US-11028090-B2 | [1,2,4]Triazolo[4,3-a]quinoxaline derivative, method for preparing same, and pharmaceutical composition for preventing or treating BET protein-related diseases, containing same as active ingredient | DONG WHA PHARM. CO., LTD. (KR) | 2021-06-08 | — | — | US | disclosed |
| US-10954436-B2 | Polynitrogen compounds and uses thereof as fluorescent chromophores | UNIVERSITE D'ORLEANS (FR) | 2021-03-23 | — | — | US | disclosed |
| US-10954436-B2 | Polynitrogen compounds and uses thereof as fluorescent chromophores | UNIVERSITE D'ORLEANS (FR) | 2021-03-23 | — | — | US | disclosed |
| US-20200039984-A1 | Novel [1,2,4]Triazolo[4,3-a]Quinoxaline Derivative, Method For Preparing Same, And Pharmaceutical Composition For Preventing Or Treating BET Protein-Related Diseases, Containing Same As Active Ingredient | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2020-02-06 | — | — | US | disclosed |
| US-20200039984-A1 | Novel [1,2,4]Triazolo[4,3-a]Quinoxaline Derivative, Method For Preparing Same, And Pharmaceutical Composition For Preventing Or Treating BET Protein-Related Diseases, Containing Same As Active Ingredient | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2020-02-06 | — | — | US | disclosed |
| US-20180194997-A1 | POLYNITROGEN COMPOUNDS AND USES THEREOF AS FLUORESCENT CHROMOPHORES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-07-12 | — | — | US | disclosed |
| US-4780464-A | CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-25 | — | — | US | disclosed |
| US-4623725-A | [1,2,4]Triazolo[4,3-a]quinoxaline-4-amine derivatives | PFIZER INC. (US) | 1986-11-18 | — | — | US | disclosed |
| EP-0107455-B1 | TRIAZOLOQUINOXALINES AS ANTIDEPRESSANTS AND ANTIFATIGUE AGENTS | PFIZER INC. (US) | 1986-07-09 | — | — | EP | disclosed |
| US-4547501-A | Method of using [1,2,4]triazolo[4,3-a]quinoxaline-4-amine derivatives as antidepressant and antifatigue agents | PFIZER INC. (US) | 1985-10-15 | — | — | US | disclosed |
| US-4495187-A | Method of using [1,2,4]triazolo[4,3-a]quinoxaline-4-amine derivatives as antidepressant and antifatigue agents | PFIZER INC. (US) | 1985-01-22 | — | — | US | disclosed |
| EP-0107455-A1 | Triazoloquinoxalines as antidepressants and antifatigue agents | PFIZER INC. (US) | 1984-05-02 | — | — | EP | disclosed |
| US-4008322-A | RICE BLAST | ELI LILLY AND COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
| US-3987196-A | FUNGISTATS | ELI LILLY AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3979387-A | PROTECTION OF PLANTS FROM FOLIAR PATHOGENS | ELI LILLY AND COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194997-A1 | POLYNITROGEN COMPOUNDS AND USES THEREOF AS FLUORESCENT CHROMOPHORES | PNN, NCL, NUCB2 | TDP1 799/4885KDM4E 4460/4885MAPT 4343/4885 |
| US-11028090-B2 | [1,2,4]Triazolo[4,3-a]quinoxaline derivative, method for preparing same, and pharmaceutical composition for preventing or treating BET protein-related diseases, containing same as active ingredient | BRD4, BET1, BRD3 | TDP1 1174/4885KDM4E 210/4885MAPT 2313/4885 |
| US-20200039984-A1 | Novel [1,2,4]Triazolo[4,3-a]Quinoxaline Derivative, Method For Preparing Same, And Pharmaceutical Composition For Preventing Or Treating BET Protein-Related Diseases, Containing Same As Active Ingredient | BRD4, BET1, BRD3 | TDP1 1199/4885KDM4E 250/4885MAPT 2456/4885 |
| US-10954436-B2 | Polynitrogen compounds and uses thereof as fluorescent chromophores | PNN, NCL, NUCB2 | TDP1 799/4885KDM4E 4460/4885MAPT 4343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.