Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | PGK1 | P00558 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29340312 | 0.79 | PGK1 (0.57) | TDP1PGK1KDM4EL3MBTL1NPSR1 | |
| SCHEMBL29340314 | 0.79 | PGK1 (0.57) | TDP1PGK1KDM4EL3MBTL1NPSR1 | |
| SCHEMBL462643 | 0.78 | TDP1 (0.58) | TDP1KDM4EL3MBTL1NPSR1RXFP1 | |
| SCHEMBL17014813 | 0.78 | KDM4E (0.70) | TDP1PGK1KDM4EL3MBTL1NPSR1 | |
| SCHEMBL6993440 | 0.76 | MAPT (0.51) | TDP1KDM4EL3MBTL1ALDH1A1POLB | |
| SCHEMBL116696 | 0.75 | TDP1 (1.00) | TDP1KDM4EL3MBTL1NPSR1RXFP1 | |
| SCHEMBL29451077 | 0.75 | TDP1 (1.00) | TDP1KDM4EL3MBTL1NPSR1RXFP1 | |
| SCHEMBL18323559 | 0.75 | TDP1 (0.54) | TDP1KDM4EL3MBTL1NPSR1RXFP1 | |
| SCHEMBL2302871 | 0.75 | RXFP1 (0.66) | TDP1KDM4EL3MBTL1NPSR1RXFP1 | |
| SCHEMBL6217678 | 0.75 | KDM4E (0.81) | TDP1PGK1KDM4EL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400505-A1 | PEPTIDE-UREA DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND APPLICATION THEREOF | Bivision Pharmaceuticals, Inc (CN) | 2024-07-17 | — | — | EP | disclosed |
| CN-107074896-B | Electroluminescent imidazoquinoxaline carbene metal complexes | UDC 爱尔兰有限责任公司 | 2021-04-13 | — | — | CN | disclosed |
| US-10784448-B2 | Electroluminescent imidazo-quinoxaline carbene metal complexes | UDC IRELAND LIMITED (IE) | 2020-09-22 | — | — | US | disclosed |
| US-10428075-B2 | Coelenterazine analogues | PROMEGA CORPORATION (US) | 2019-10-01 | — | — | US | disclosed |
| EP-3466957-A1 | OLED COMPRISING AN ELECTROLUMINESCENT IMIDAZO-QUINOXALINE CARBENE METAL COMPLEXES | UDC Ireland Limited (IE) | 2019-04-10 | — | — | EP | disclosed |
| EP-3186264-B1 | ELECTROLUMINESCENT IMIDAZO-QUINOXALINE CARBENE METAL COMPLEXES | UDC IRELAND LTD (IE) | 2018-11-28 | — | — | EP | disclosed |
| US-20180223184-A1 | ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) | 2018-08-09 | — | — | US | disclosed |
| US-20170237020-A1 | Electroluminescent Imidazo-Quinoxaline Carbene Metal Complexes | BASF SE (DE) | 2017-08-17 | — | — | US | disclosed |
| EP-3186264-A1 | ELECTROLUMINESCENT IMIDAZO-QUINOXALINE CARBENE METAL COMPLEXES | UDC Ireland Limited (IE) | 2017-07-05 | — | — | EP | disclosed |
| EP-3167887-A1 | ARYL AMINE SUBSTITUTED QUINOXALINE USED AS ANTICANCER DRUGS | Chen, Kuenfeng (TW) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016020516-A1 | ELECTROLUMINESCENT IMIDAZO-QUINOXALINE CARBENE METAL COMPLEXES | BASF SE (DE) | 2016-02-11 | — | — | WO | disclosed |
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10428075-B2 | Coelenterazine analogues | GLB1, SI, TCF7L2 | TDP1 3852/4885PGK1 3305/4885KDM4E 3302/4885 |
| US-10784448-B2 | Electroluminescent imidazo-quinoxaline carbene metal complexes | OCIAD1, OCIAD2, OXER1 | TDP1 4129/4885PGK1 2888/4885KDM4E 3834/4885 |
| US-20170237020-A1 | Electroluminescent Imidazo-Quinoxaline Carbene Metal Complexes | OCIAD1, OCIAD2, OXER1 | TDP1 4129/4885PGK1 2888/4885KDM4E 3834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.