SCHEMBL4626645

SCHEMBL4626645

CCOC(=O)c1cc(Cl)c(CC)cc1C(=O)OCC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.51
CYP4A11 Q02928 1/20 0.51
BAZ2B Q9UIF8 1/20 0.51
BAZ2A Q9UIF9 1/20 0.51
TSHR P16473 1/20 0.50
CA1 P00915 5/20 0.47
CA2 P00918 5/20 0.47
CA12 O43570 4/20 0.47
CA9 Q16790 4/20 0.47
MAPK1 P28482 2/20 0.46
GAA P10253 1/20 0.46
CA7 P43166 3/20 0.46
CA14 Q9ULX7 3/20 0.46
ALDH1A1 P00352 3/20 0.45
MAPT P10636 2/20 0.45
LMNA P02545 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
PDE3B Q13370 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6911857 0.89 CYP4F2 (0.43) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL4628188 0.89 CYP4F2 (0.43) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL4628309 0.89 TSHR (0.49) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL4625616 0.89 TSHR (0.49) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL4627094 0.89 CYP4F2 (0.43) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL4628255 0.89 CYP4F2 (0.43) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL236240 0.88 CYP4F2 (0.57) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL4627602 0.86 TSHR (0.59) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL6912804 0.84 CYP4F2 (0.40) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL4627190 0.84 CYP4F2 (0.40) CYP4F2CYP4A11BAZ2BBAZ2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1188739-B1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO LTD (JP) 2008-08-13 EP disclosed
EP-1209172-B1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2008-07-02 EP disclosed
US-6770586-B2 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD. (JP) 2004-08-03 US disclosed
US-6670497-B2 Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst TOHO TITANIUM CO., LTD. (JP) 2003-12-30 US disclosed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 EP disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX CYP4F2 220/4885CYP4A11 259/4885BAZ2B 3643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.