Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 7/20 | 0.36 |
| ▸ | MMP9 | P14780 | 6/20 | 0.36 |
| ▸ | MMP13 | P45452 | 6/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | MMP7 | P09237 | 3/20 | 0.36 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | MMP14 | P50281 | 3/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | MMP10 | P09238 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346119 | 0.74 | RXRA (0.42) | PDE4APDE4BPDE4CPDE4DMMP1 | |
| SCHEMBL345064 | 0.72 | SMN1; SMN2 (0.42) | PDE4APDE4BPDE4CPDE4DMMP1 | |
| SCHEMBL29834917 | 0.72 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DMMP1 | |
| SCHEMBL345897 | 0.71 | MMP1 (0.49) | PDE4APDE4BPDE4CPDE4DMMP1 | |
| SCHEMBL26403963 | 0.68 | XDH (0.39) | ADRB3ADRB1 | |
| Hydrochloric Acid SCHEMBL26127342 | 0.67 | XDH (0.38) | ADRB3ADRB1 | |
| SCHEMBL26405920 | 0.66 | SCN9A (0.39) | — | |
| Hydrochloric Acid SCHEMBL26126752 | 0.66 | SCN9A (0.38) | — | |
| SCHEMBL24440122 | 0.65 | SRD5A1 (0.41) | PPARGPPARA | |
| SCHEMBL16313316 | 0.64 | MMP1 (0.76) | MMP1MMP9MMP13ADAM17MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012320-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENIUM PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |