SCHEMBL4626797

SCHEMBL4626797

CCCCn1c(=O)[nH]c(=O)c2ncn(CC)c21

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 4/20 0.65
BRD2 P25440 2/20 0.65
BRD3 Q15059 2/20 0.65
BRDT Q58F21 2/20 0.65
ALDH1A1 P00352 3/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
PDE4A P27815 7/20 0.54
ADORA2A P29274 7/20 0.54
PDE4B Q07343 7/20 0.54
PDE4C Q08493 7/20 0.54
PDE4D Q08499 7/20 0.54
MAPT P10636 1/20 0.44
ATM Q13315 1/20 0.44
ADORA2B P29275 2/20 0.44
ADORA3 P0DMS8 1/20 0.44
KDM4E B2RXH2 4/20 0.42
HPGD P15428 1/20 0.42
GAA P10253 2/20 0.42
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4623458 0.91 PDE4A (0.63) BRD4BRD2BRD3BRDTALDH1A1
SCHEMBL6251096 0.90 PDE4A (0.64) BRD4BRD2BRD3BRDTALDH1A1
SCHEMBL190991 0.87 ALDH1A1 (0.53) BRD4BRD2BRD3BRDTALDH1A1
SCHEMBL3115743 0.86 ALDH1A1 (0.51) BRD4BRD2BRD3BRDTALDH1A1
SCHEMBL3990425 0.85 PDE4A (0.57) BRD4BRD2BRD3BRDTALDH1A1
SCHEMBL4796600 0.80 PDE4A (0.47) BRD4BRD2BRD3BRDTALDH1A1
SCHEMBL19066317 0.79 BRD4 (1.00) BRD4BRD2BRD3BRDTALDH1A1
SCHEMBL4621714 0.78 PDE4A (0.45) BRD4BRD2BRD3BRDTALDH1A1
SCHEMBL27483073 0.76 KMT2A (0.48) BRD4BRD2BRD3BRDTALDH1A1
SCHEMBL7457891 0.74 MEN1 (1.00) BRD4BRD2BRD3BRDTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904020-A2 NEW SLIMMING COSMETIC COMPOSITIONS Sederma S.A.S. (FR) 2008-04-02 EP disclosed
WO-2007010478-A2 SLIMMING COSMETIC COMPOSITIONS SEDERMA (FR) 2007-01-25 WO disclosed