Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 10/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.63 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.63 |
| ▸ | BRD4 | O60885 | 4/20 | 0.53 |
| ▸ | BRD2 | P25440 | 2/20 | 0.53 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.53 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PDE1A | P54750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4626797 | 0.91 | BRD4 (0.65) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL6251096 | 0.90 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL3990425 | 0.88 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL4796600 | 0.82 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL8358995 | 0.80 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL4621714 | 0.80 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL27175954 | 0.79 | HSD17B10 (0.48) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL3115743 | 0.78 | ALDH1A1 (0.51) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL190991 | 0.78 | ALDH1A1 (0.53) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL21381257 | 0.78 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904020-A2 | NEW SLIMMING COSMETIC COMPOSITIONS | Sederma S.A.S. (FR) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007010478-A2 | SLIMMING COSMETIC COMPOSITIONS | SEDERMA (FR) | 2007-01-25 | — | — | WO | disclosed |