Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL152823 | 0.85 | THRB (0.40) | TSHRTHRBPAOXALDH1A1RAD52 | |
| SCHEMBL28191330 | 0.84 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27236209 | 0.83 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28854100 | 0.83 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14820457 | 0.82 | TSHR (0.42) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28258329 | 0.82 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8975046 | 0.82 | THRB (0.42) | TSHRTHRBPOLBAPEX1HTT | |
| Sulfuric Acid SCHEMBL28013696 | 0.82 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2414790 | 0.81 | THRB (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL951167 | 0.81 | THRB (0.39) | TSHRTHRBPAOXALDH1A1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541498-B2 | Lubricious coatings for medical devices | BIOINTERACTIONS LTD. (GB) | 2013-09-24 | — | — | US | claimed |
| US-8329382-B2 | Method of processing elements with coalesced particles | EASTMAN KODAK COMPANY (US) | 2012-12-11 | — | — | US | claimed |
| US-20110053089-A1 | METHOD OF PROCESSING ELEMENTS WITH COALESCED PARTICLES | QUALEX INC. | 2011-03-03 | — | — | US | claimed |
| WO-2008106323-A2 | A HIGH THROUGHPUT SCREENING METHOD AND APPARATUS TO PRODUCE MODIFIED POLYMERS PARTICULARLY MEMBRANES | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2008-09-04 | — | — | WO | claimed |
| US-12359026-B2 | In situ gelling zwitterionic hydrogel compositions, and methods of use thereof | MCMASTER UNIVERSITY (CA) | 2025-07-15 | — | — | US | disclosed |
| US-12208116-B2 | Multi-functional hemocompatible porous bead sorbent for removing protein based toxins and potassium from biological fluids | CYTOSORBENTS, INC. (US) | 2025-01-28 | — | — | US | disclosed |
| US-20240026333-A1 | STABILITY AND ACTIVITY OF ENZYMES BY IMMOBILIZATION | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2024-01-25 | — | — | US | disclosed |
| US-20240016830-A1 | Multi-Functional Hemocompatible Porous Bead Sorbent For Removing Protein Based Toxins And Potassium From Biological Fluids | AVENUE CAPITAL MANAGEMENT II, L.P. | 2024-01-18 | — | — | US | disclosed |
| US-11723916-B2 | Multi-functional hemocompatible porous polymer bead sorbent for removing protein based toxins and potassium from biological fluids | CYTOSORBENTS CORPORATION (US) | 2023-08-15 | — | — | US | disclosed |
| US-20230220166-A1 | IN SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF | MCMASTER UNIVERSITY (CA) | 2023-07-13 | — | — | US | disclosed |
| EP-4153664-A1 | IN SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF | McMaster University (CA) | 2023-03-29 | — | — | EP | disclosed |
| US-20220334123-A1 | SYSTEMS FOR PROTEIN CORONA ANALYSIS | SEER, INC. | 2022-10-20 | — | — | US | disclosed |
| WO-2008106323-A2 | A HIGH THROUGHPUT SCREENING METHOD AND APPARATUS TO PRODUCE MODIFIED POLYMERS PARTICULARLY MEMBRANES | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2008-09-04 | — | — | WO | disclosed |
| EP-1923703-A2 | A method for producing a biosensor having a covalently bound thin polymeric coat | FUJIFILM Corporation (JP) | 2008-05-21 | — | — | EP | disclosed |
| US-20070203285-A1 | Composition and use | HODGE DAVID J | 2007-08-30 | — | — | US | disclosed |
| EP-1826563-A1 | Biosensor | Fujifilm Corporation (JP) | 2007-08-29 | — | — | EP | disclosed |
| EP-1790984-A2 | A method for producing a biosensor having a covalently bound thin polymeric coat | Fujifilm Corporation (JP) | 2007-05-30 | — | — | EP | disclosed |
| US-7217759-B2 | Composition and use | ARCH UK BIOCIDES LIMITED (GB) | 2007-05-15 | — | — | US | disclosed |
| EP-1696235-A1 | Biosensor | FUJI PHOTO FILM CO., LTD. (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-20050008534-A1 | Composition and use | ARCH UK BIOCIDES | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050008534-A1 | Composition and use | TST, TH, ARG1 | TSHR 729/4885THRB 1231/4885POLB 2190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.