Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | F12 | P00748 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MGAM | O43451 | 2/20 | 0.53 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.53 |
| ▸ | SI | P14410 | 2/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | FOS | P01100 | 1/20 | 0.49 |
| ▸ | JUN | P05412 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462692 | 1.00 | NPSR1 (0.60) | NPSR1MAPTF12GAAMGAM | |
| SCHEMBL463198 | 0.87 | MAPT (0.70) | NPSR1MAPTF12GAAMGAM | |
| SCHEMBL463197 | 0.87 | MAPT (0.70) | NPSR1MAPTF12GAAMGAM | |
| SCHEMBL461243 | 0.82 | MAPT (0.74) | NPSR1MAPTF12GAAMGAM | |
| SCHEMBL461244 | 0.82 | MAPT (0.74) | NPSR1MAPTF12GAAMGAM | |
| SCHEMBL15053260 | 0.82 | JUN (0.54) | NPSR1MAPTF12GAAMGAM | |
| SCHEMBL15053261 | 0.82 | JUN (0.54) | NPSR1MAPTF12GAAMGAM | |
| SCHEMBL15052681 | 0.81 | MAPT (0.60) | NPSR1MAPTF12GAAMGAM | |
| SCHEMBL15052680 | 0.81 | MAPT (0.60) | NPSR1MAPTF12GAAMGAM | |
| SCHEMBL15053022 | 0.79 | MAPT (0.57) | NPSR1MAPTF12GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853276-B2 | Guanidine derivatives in cinnamic series | PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE (FR) | 2014-10-07 | — | — | US | disclosed |
| EP-2614046-B1 | NOVEL GUANIDINE DERIVATIVES IN THE CINNAMIC SERIES | PROD CHIM AUXILIAIRES ET DE SYNTHESE (FR) | 2014-08-20 | — | — | EP | disclosed |
| EP-2614046-A1 | NOVEL GUANIDINE DERIVATIVES IN THE CINNAMIC SERIES | Produits Chimiques Auxiliaires et de Synthese (FR) | 2013-07-17 | — | — | EP | disclosed |
| US-20130165507-A1 | NEW GUANIDINE DERIVATIVES IN CINNAMIC SERIES | PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE (FR) | 2013-06-27 | — | — | US | disclosed |
| WO-2012032257-A1 | NOVEL GUANIDINE DERIVATIVES IN THE CINNAMIC SERIES | PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE (FR) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165507-A1 | NEW GUANIDINE DERIVATIVES IN CINNAMIC SERIES | GMPS, UNG, AGER | NPSR1 4424/4885MAPT 2457/4885F12 4308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.