SCHEMBL4627211

SCHEMBL4627211

CCCC(CC)OC(=O)c1cc(CC)c(Br)cc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.46
PRKCD Q05655 2/20 0.46
HSD17B10 Q99714 2/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
PPARG P37231 2/20 0.32
PPARA Q07869 2/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30
GABRP O00591 1/20 0.30
GABRD O14764 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB1 P18505 1/20 0.30
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRA5 P31644 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4627869 1.00 PRKCA (0.46) PRKCAPRKCDHSD17B10TSHRALDH1A1
SCHEMBL4627210 0.95 PRKCA (0.50) PRKCAPRKCDTSHRALDH1A1L3MBTL1
SCHEMBL4641116 0.92 PRKCA (0.50) PRKCAPRKCDHSD17B10TSHRALDH1A1
SCHEMBL4640593 0.90 PRKCA (0.51) PRKCAPRKCDHSD17B10TSHRALDH1A1
SCHEMBL4640506 0.90 PRKCA (0.36) PRKCAPRKCDHSD17B10TSHRALDH1A1
SCHEMBL4626604 0.87 PRKCA (0.46) PRKCAPRKCDHSD17B10TSHRALDH1A1
SCHEMBL4627360 0.87 PRKCA (0.46) PRKCAPRKCDHSD17B10TSHRALDH1A1
SCHEMBL4641115 0.86 PRKCA (0.55) PRKCAPRKCDHSD17B10TSHRALDH1A1
SCHEMBL18628681 0.86 PRKCA (0.55) PRKCAPRKCDHSD17B10TSHRALDH1A1
SCHEMBL4643402 0.86 PRKCA (0.45) PRKCAPRKCDHSD17B10TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1188739-B1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO LTD (JP) 2008-08-13 EP disclosed
EP-1209172-B1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2008-07-02 EP disclosed
US-6770586-B2 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD. (JP) 2004-08-03 US disclosed
US-6670497-B2 Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst TOHO TITANIUM CO., LTD. (JP) 2003-12-30 US disclosed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 EP disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX PRKCA 1200/4885PRKCD 552/4885HSD17B10 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.