Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | LTA4H | P09960 | 4/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685845 | 0.90 | AAK1 (0.46) | SLC6A2PTGS1AAK1CYP3A4CYP2C19 | |
| SCHEMBL3173896 | 0.82 | SLC6A2 (0.58) | SLC6A2PTGS1ADRB3ADRB2ADRB1 | |
| SCHEMBL10922516 | 0.76 | LMNA (0.67) | SLC6A2PTGS1ADRB3ADRB2ADRB1 | |
| SCHEMBL11277643 | 0.75 | SLC6A2 (0.54) | SLC6A2PTGS1ADRB3ADRB2ADRB1 | |
| SCHEMBL6937523 | 0.73 | FFAR1 (0.54) | SLC6A2PTGS1ADRB3ADRB2ADRB1 | |
| SCHEMBL8912305 | 0.73 | FFAR1 (0.54) | SLC6A2PTGS1ADRB3ADRB2ADRB1 | |
| SCHEMBL2473518 | 0.73 | SLC6A2 (0.53) | SLC6A2PTGS1ADRB3ADRB2ADRB1 | |
| SCHEMBL19531152 | 0.73 | HTT (0.57) | SLC6A2PTGS1ADRB3ADRB2ADRB1 | |
| SCHEMBL1854910 | 0.72 | SLC6A2 (0.51) | SLC6A2PTGS1ADRB3ADRB2ADRB1 | |
| SCHEMBL8765752 | 0.72 | SLC6A2 (0.51) | SLC6A2PTGS1ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874264-A1 | ANTIMICROBIAL FORMULATIONS | Syntopix limited (GB) | 2008-01-09 | — | — | EP | disclosed |
| EP-1865915-A1 | ANTIMICROBIAL AGENTS | Syntopix limited (GB) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006100496-A1 | ANTIMICROBIAL AGENTS | SYNTOPIX LIMITED (GB) | 2006-09-28 | — | — | WO | disclosed |
| WO-2006100495-A1 | FORMULATIONS | SYNTOPIX LIMITED (GB) | 2006-09-28 | — | — | WO | disclosed |