Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.45 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937523 | 0.82 | FFAR1 (0.54) | SLC6A2PTGS1LTA4HADRB3ADRB2 | |
| SCHEMBL8912305 | 0.82 | FFAR1 (0.54) | SLC6A2PTGS1LTA4HADRB3ADRB2 | |
| SCHEMBL5661525 | 0.82 | SIGMAR1 (0.53) | CYP1A2MEN1KMT2AKCNH2MAPK1 | |
| SCHEMBL5663771 | 0.82 | SIGMAR1 (0.53) | CYP1A2MEN1KMT2AKCNH2MAPK1 | |
| SCHEMBL5662052 | 0.81 | TSHR (0.40) | CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL5664562 | 0.81 | TSHR (0.40) | CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL9721664 | 0.81 | TSHR (0.40) | CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL8765745 | 0.81 | FFAR1 (0.39) | PTGS1LMNAAR | |
| SCHEMBL3173896 | 0.79 | SLC6A2 (0.58) | SLC6A2PTGS1LTA4HADRB3ADRB2 | |
| SCHEMBL7785554 | 0.79 | LTA4H (0.50) | SLC6A2PTGS1LTA4HADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |