Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GYS1 | P13807 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28431087 | 0.83 | GYS1 (0.47) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL27727564 | 0.80 | BACE1 (0.42) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL1513817 | 0.78 | BACE1 (0.52) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL27967295 | 0.77 | ALDH1A1 (0.41) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL27587157 | 0.77 | PTPN1 (0.44) | HPGDLMNAMEN1MAPTKMT2A | |
| SCHEMBL5132773 | 0.77 | ALDH1A1 (0.56) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL321984 | 0.76 | BACE1 (0.42) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL29351964 | 0.76 | BACE1 (0.50) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL27692000 | 0.76 | BACE1 (0.50) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL2654207 | 0.76 | BACE1 (0.38) | BACE1ALOX5ALDH1A1HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917240-A1 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007024922-A1 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2007-03-01 | — | — | WO | disclosed |