SCHEMBL4628628

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4625674	0.88	KDM4E (0.38)	KDM4ENPSR1RXFP1TSHRALDH1A1
	SCHEMBL4628433	0.88	ESR1 (0.43)	TSHRALDH1A1MAPK1HSD17B10LMNA
	SCHEMBL4628680	0.87	TSHR (0.38)	KDM4EADORA3TSHRALDH1A1SMN1; SMN2
	SCHEMBL4626624	0.86	MAOB (0.39)	KDM4ENPSR1RXFP1TSHRALDH1A1
	SCHEMBL4626753	0.85	CYP4F2 (0.39)	ADORA3TSHRALDH1A1MAPK1GAA
	SCHEMBL4626485	0.85	PDE3B (0.39)	KDM4ETSHRALDH1A1SMN1; SMN2MAPK1
	SCHEMBL4627235	0.83	TSHR (0.37)	KDM4ETSHRALDH1A1SMN1; SMN2MAPK1
	SCHEMBL4625610	0.83	MAPK1 (0.39)	KDM4ENPSR1RXFP1ADORA3TSHR
	SCHEMBL6912282	0.82	ALDH1A1 (0.38)	KDM4ENPSR1RXFP1ADORA3TSHR
	SCHEMBL4627306	0.82	TSHR (0.41)	KDM4ENPSR1RXFP1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.