Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471697 | 0.94 | FFAR1 (0.43) | LTB4RPTGER2FFAR1FFAR4PTPN7 | |
| SCHEMBL1471098 | 0.92 | LTB4R (0.50) | LTB4RPTGER2FFAR1FFAR4S1PR1 | |
| SCHEMBL5859870 | 0.81 | ALDH1A1 (0.47) | LTB4RPTGER2 | |
| SCHEMBL1471110 | 0.81 | PTGER2 (0.43) | LTB4RPTGER2S1PR1S1PR3PTGER4 | |
| SCHEMBL9453929 | 0.76 | CYSLTR2 (0.61) | LTB4RPTGER2FFAR1FFAR4S1PR1 | |
| SCHEMBL11601260 | 0.74 | FFAR4 (0.65) | PTGER2FFAR1FFAR4 | |
| SCHEMBL11602007 | 0.74 | FFAR4 (0.65) | PTGER2FFAR1FFAR4 | |
| SCHEMBL11599827 | 0.73 | HMGCR (0.55) | EPHX2FFAR1FFAR4PTPN7HMGCR | |
| SCHEMBL12827664 | 0.73 | S1PR1 (0.67) | LTB4RPTGER2FFAR1FFAR4S1PR1 | |
| SCHEMBL4628656 | 0.72 | PTGER2 (0.42) | LTB4REPHX2PTGER2PTPN7HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917238-A2 | SULFONAMIDES | Allergan, Inc. (US) | 2008-05-07 | — | — | EP | claimed |
| WO-2007024860-A2 | SULFONAMIDES | ALLERGAN, INC. (US) | 2007-03-01 | — | — | WO | claimed |