SCHEMBL4628866

SCHEMBL4628866

CC(C1CCCCN1)N1CCNCC1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 9/20 0.39
SLC6A2 P23975 7/20 0.39
SLC6A4 P31645 7/20 0.39
SIGMAR1 Q99720 1/20 0.36
DHFR P00374 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27980514 0.94 SIGMAR1 (0.34) SLC6A3SLC6A2SLC6A4SIGMAR1
SCHEMBL6968694 0.87 SLC6A3 (0.40) SLC6A3SLC6A2SLC6A4DHFR
SCHEMBL28078048 0.85 SIGMAR1 (0.33) SIGMAR1
SCHEMBL6079957 0.81 SLC6A2 (0.34) SLC6A3SLC6A2SLC6A4
SCHEMBL7127976 0.78 SLC6A2 (0.35) SLC6A3SLC6A2SLC6A4
SCHEMBL11181433 0.76 SIGMAR1 (0.42) SIGMAR1
SCHEMBL7129871 0.76 SLC6A3 (0.34) SLC6A3SLC6A2SLC6A4SIGMAR1
SCHEMBL27318125 0.76 CHRM2 (0.30)
SCHEMBL28078008 0.75 HTR6 (0.36) SLC6A3SLC6A2SLC6A4
SCHEMBL6394777 0.75 SIGMAR1 (0.44) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN disclosed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN disclosed
EP-1771425-B1 2-CARBAMIDE-4-PHENYLTHIAZOLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI AVENTIS (FR) 2008-05-14 EP disclosed
CN-101035783-A Urea derivatives as calcium channel blockers NEUROMED PHARMACEUTICALS LTD (CA) 2007-09-12 CN disclosed
CN-101001847-A 2-Urea-4-phenylthiazole derivatives, preparation method and therapeutic use thereof SANOFI AVENTIS (FR) 2007-07-18 CN disclosed