Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27188909 | 0.82 | CYP3A4 (0.45) | CYP3A4ALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL547428 | 0.78 | MEN1 (0.44) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL18101494 | 0.76 | SMN1; SMN2 (0.45) | CYP3A4ALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL18101499 | 0.73 | CYP3A4 (0.38) | CYP3A4ALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL3136514 | 0.72 | ALDH1A1 (0.40) | ALDH1A1LMNA | |
| SCHEMBL14214940 | 0.70 | HDAC9 (0.47) | CYP3A4ALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL9405305 | 0.70 | CA1 (0.45) | CYP3A4ALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL1654890 | 0.69 | ALDH1A1 (0.43) | CYP3A4ALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL7196359 | 0.68 | CYP3A4 (0.42) | CYP3A4ALDH1A1MAPTTSHRHSD17B10 | |
| Ethane SCHEMBL28085459 | 0.67 | CYP3A4 (0.92) | CYP3A4ALDH1A1MAPTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181550-B1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | BAYER IP GMBH (DE) | 2019-11-20 | — | — | EP | disclosed |
| EP-3181550-A1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | Bayer Intellectual Property GmbH (DE) | 2017-06-21 | — | — | EP | disclosed |
| US-20160023987-A1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-28 | — | — | US | disclosed |
| US-9173399-B2 | Benzocycloalkenes as antifungal agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-03 | — | — | US | disclosed |
| EP-2595961-A2 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | Bayer Intellectual Property GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| US-20130123322-A1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-16 | — | — | US | disclosed |
| WO-2012010579-A2 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160023987-A1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | CYP51A1, ERG28, CBR1 | CYP3A4 30/4885ALDH1A1 2101/4885MAPT 3160/4885 |
| US-20130123322-A1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | CYP51A1, ERG28, CBR1 | CYP3A4 30/4885ALDH1A1 2101/4885MAPT 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.