Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 6/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 6/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 6/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | TPH1 | P17752 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16814949 | 0.79 | NCF1 (0.46) | NCF1GFERACHECHRM4HRH3 | |
| SCHEMBL29512584 | 0.79 | PBRM1 (0.54) | SMARCA2SMARCA4PBRM1NR1I2NR1H3 | |
| SCHEMBL23043568 | 0.79 | PBRM1 (0.54) | SMARCA2SMARCA4PBRM1NR1I2NR1H3 | |
| SCHEMBL2107135 | 0.76 | BCHE (0.47) | SMARCA2SMARCA4PBRM1NR1I2NR1H3 | |
| SCHEMBL5153091 | 0.75 | HRH3 (0.45) | SMARCA2SMARCA4PBRM1NR1I2NR1H3 | |
| SCHEMBL16792864 | 0.75 | MAPT (0.43) | SMARCA2SMARCA4PBRM1NR1I2NR1H3 | |
| SCHEMBL16814971 | 0.74 | MAPT (0.42) | SMARCA2SMARCA4PBRM1NR1I2NR1H3 | |
| SCHEMBL9424277 | 0.73 | MEN1 (0.54) | SMARCA2SMARCA4PBRM1NR1I2NR1H3 | |
| SCHEMBL26288710 | 0.73 | KMT2A (0.51) | BCHEACHEARLMNACHRM4 | |
| SCHEMBL26288600 | 0.73 | KMT2A (0.51) | BCHEACHEARLMNACHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456195-B2 | Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-25 | — | — | US | disclosed |
| EP-1910298-A2 | PHENYLGLYCINAMIDE AND PYRIDYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | Brystol-Myers Squibb Company (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007002313-A2 | PHENYLGLYCINAMIDE AND PYRIDYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20070003539-A1 | Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070003539-A1 | Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants | F12, F11, F7 | NCF1 4468/4885SMARCA2 3622/4885SMARCA4 3855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.