Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.57 |
| ▸ | NQO2 | P16083 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GABRP | O00591 | 5/20 | 0.51 |
| ▸ | GABRD | O14764 | 5/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.51 |
| ▸ | GABRE | P78334 | 5/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425209 | 0.86 | NQO2 (0.55) | NQO2MEN1KMT2AGABRPGABRD | |
| SCHEMBL3676424 | 0.85 | GPR84 (0.58) | GPR84NQO2MEN1KMT2AGABRP | |
| SCHEMBL30844121 | 0.85 | NQO2 (0.54) | NQO2MEN1KMT2AGABRPGABRD | |
| SCHEMBL28902306 | 0.82 | NPC1 (0.61) | GPR84NQO2MEN1KMT2AMAPT | |
| SCHEMBL29251331 | 0.81 | KMT2A (0.57) | NQO2MEN1KMT2AGABRPGABRD | |
| SCHEMBL29251301 | 0.80 | NQO2 (0.46) | NQO2MEN1KMT2AGABRPGABRD | |
| SCHEMBL13302316 | 0.80 | HTR7 (0.51) | GPR84NQO2MEN1KMT2AGABRP | |
| SCHEMBL8544378 | 0.80 | GPR84 (0.54) | GPR84NQO2MEN1KMT2AGABRP | |
| SCHEMBL31744889 | 0.79 | GPR84 (0.68) | GPR84MEN1KMT2AHTR2A | |
| SCHEMBL27929617 | 0.79 | NQO2 (0.61) | GPR84NQO2MEN1KMT2AGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843548-A | Benzyl indole HDAC inhibitor and pharmaceutical application thereof | 南京医科大学 | 2024-04-09 | — | — | CN | disclosed |
| EP-1919866-A2 | SUBSTITUTED INDOLES AND USE THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007022321-A2 | SUBSTITUTED INDOLES AND USE THEREOF | WYETH (US) | 2007-02-22 | — | — | WO | disclosed |