Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631326 | 1.00 | NAAA (0.50) | NAAALMNANPC1SMN1; SMN2NFKB1 | |
| Bromide SCHEMBL11348026 | 0.98 | NAAA (0.49) | NAAALMNANPC1SMN1; SMN2NFKB1 | |
| Bromide SCHEMBL28663673 | 0.98 | NAAA (0.49) | NAAALMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL7560833 | 0.92 | HDAC3 (0.45) | NAAALMNANPC1SMN1; SMN2NFKB1 | |
| Bromide SCHEMBL11344288 | 0.91 | HDAC3 (0.44) | NAAALMNANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL11412668 | 0.81 | CES2 (0.58) | NAAALMNAMAPTCES2CES1 | |
| SCHEMBL164610 | 0.81 | CES2 (0.58) | NAAALMNAMAPTCES2CES1 | |
| SCHEMBL3803931 | 0.81 | CES2 (0.58) | NAAALMNAMAPTCES2CES1 | |
| SCHEMBL10625164 | 0.81 | CES2 (0.58) | NAAALMNAMAPTCES2CES1 | |
| SCHEMBL7796974 | 0.81 | CES2 (0.58) | NAAALMNAMAPTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636309-B1 | COMPOSITIONS AND METHOD FOR IMPROVING THE PROCESSING OF POLYMER COMPOSITES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-05-14 | — | — | EP | claimed |