SCHEMBL46300

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14892272	1.00	TP53 (0.42)	TP53ALDH1A1ANPEPENPEPGAA
	SCHEMBL17872341	1.00	TP53 (0.42)	TP53ALDH1A1ANPEPENPEPGAA
	SCHEMBL17317581	0.89	CHRNB2 (0.39)	TP53ALDH1A1ANPEPENPEPGAA
	SCHEMBL28468627	0.84	BRD4 (0.42)	TP53ALDH1A1GAASMN1; SMN2PPM1B
	SCHEMBL20501862	0.82	TP53 (0.41)	TP53ALDH1A1GAASMN1; SMN2HPGD
	SCHEMBL20501859	0.82	TP53 (0.41)	TP53ALDH1A1GAASMN1; SMN2HPGD
	SCHEMBL17317471	0.82	CHRNB2 (0.47)	TP53ALDH1A1GAASLC6A1GABRA5
	SCHEMBL358775	0.81	GAA (0.47)	TP53ALDH1A1GAASMN1; SMN2PPM1B
	SCHEMBL14305169	0.81	TP53 (0.46)	TP53ALDH1A1GAASMN1; SMN2PPM1B
	SCHEMBL5543322	0.81	GAA (0.47)	TP53ALDH1A1GAASMN1; SMN2PPM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.