Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | HTR7 | P34969 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 7/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629546 | 0.91 | CYP3A4 (0.50) | CYP3A4CYP2D6HTR7DRD2HTR2A | |
| SCHEMBL4630164 | 0.89 | CYP3A4 (0.56) | CYP3A4CYP2D6HTR7DRD2HTR2A | |
| SCHEMBL4628929 | 0.89 | KCNH2 (0.56) | CYP3A4CYP2D6HTR7DRD2HTR2A | |
| SCHEMBL4628912 | 0.88 | CYP3A4 (0.41) | CYP3A4CYP2D6HTR7DRD2HTR2A | |
| SCHEMBL2223601 | 0.83 | CYP3A4 (0.55) | CYP3A4CYP2D6HTR7DRD2HTR2A | |
| Hydrochloric Acid SCHEMBL2224607 | 0.82 | CYP3A4 (0.54) | CYP3A4CYP2D6HTR7DRD2HTR2A | |
| SCHEMBL4629547 | 0.81 | CA2 (0.45) | CYP3A4CYP2D6HTR7DRD2HTR2A | |
| SCHEMBL4630178 | 0.81 | HTR6 (0.44) | CYP3A4CYP2D6HTR7DRD2HTR2A | |
| SCHEMBL4629379 | 0.79 | CYP3A4 (0.54) | CYP3A4CYP2D6HTR7DRD2HTR2A | |
| SCHEMBL16986597 | 0.79 | CYP3A4 (0.57) | CYP3A4CYP2D6HTR7DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200792-A1 | RUTHENIUM-SPHINGOMYELIN COMPLEXES AND METHODS FOR THEIR USE IN THE TREATMENT OF TUMORS | GARNETT MCKEEN LAB, INC. (US) | 2017-11-23 | — | — | WO | disclosed |
| EP-2870256-A1 | INACTIVATION OF A PRODUCTION STRAIN USING A FATTY ACID | Novozymes A/S (DK) | 2015-05-13 | — | — | EP | disclosed |
| EP-2814327-A1 | FOOD COMPOSITION COMPRISING VITAMIN K AND SATURATED FAT AND ITS USE | FrieslandBrands B.V. (NL) | 2014-12-24 | — | — | EP | disclosed |
| WO-2014006040-A1 | INACTIVATION OF A PRODUCTION STRAIN USING A FATTY ACID | NOVOZYMES A/S (DK) | 2014-01-09 | — | — | WO | disclosed |
| WO-2013122465-A1 | FOOD COMPOSITION COMPRISING VITAMIN K AND SATURATED FAT AND ITS USE | FRIESLAND BRANDS B.V. (NL) | 2013-08-22 | — | — | WO | disclosed |
| EP-1919896-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | Suven Life Sciences Limited (IN) | 2008-05-14 | — | — | EP | disclosed |
| EP-1917007-A2 | INHIBITORS OF ANOREXIC LIPID HYDROLYSIS FOR THE TREATMENT OF EATING DISORDERS | Rheoscience A/S (DK) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007020652-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007006319-A2 | INHIBITORS OF ANOREXIC LIPID HYDROLYSIS FOR THE TREATMENT OF EATING DISORDERS | RHEOSCIENCE A/S (DK) | 2007-01-18 | — | — | WO | disclosed |