Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630078 | 0.79 | NOTUM (0.47) | HPGDTP53LMNAKDM4ETSHR | |
| SCHEMBL10524329 | 0.78 | HTR2A (0.45) | HTR2AHTR2CMAPTTHRBFABP4 | |
| SCHEMBL4175475 | 0.74 | TFPI2 (0.48) | HTR2AHTR2CMAPTTHRBFABP4 | |
| SCHEMBL4630556 | 0.73 | SLC6A2 (0.36) | MAPTFABP4HPGDKDM4E | |
| SCHEMBL4709901 | 0.72 | HTR2A (0.38) | HTR2AHTR2CFABP4LMNAKDM4E | |
| SCHEMBL28980350 | 0.71 | FABP4 (0.41) | HTR2AHTR2CMAPTTHRBFABP4 | |
| SCHEMBL19674140 | 0.71 | ATM (0.57) | HTR2AHTR2CMAPTHPGDTP53 | |
| SCHEMBL5230412 | 0.69 | CLK1 (0.37) | HPGDTP53LMNAKDM4EGLA | |
| SCHEMBL28470000 | 0.69 | TUBB1 (0.49) | HTR2CMAPTFABP4TFPI2HPGD | |
| SCHEMBL6901863 | 0.68 | TFPI2 (0.55) | HTR2AHTR2CMAPTTHRBFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799797-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-05-14 | — | — | EP | claimed |