Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 4/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.54 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.54 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.54 |
| ▸ | GABRP | O00591 | 1/20 | 0.54 |
| ▸ | GABRD | O14764 | 1/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.54 |
| ▸ | GABRE | P78334 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.54 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.54 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630766 | 0.86 | — | — | |
| SCHEMBL3947564 | 0.83 | GABRA5 (0.52) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL5415862 | 0.81 | — | — | |
| SCHEMBL3768027 | 0.78 | GABRA5 (0.52) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL2409709 | 0.78 | GABRA1 (0.52) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL3979914 | 0.78 | GABRA5 (0.52) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL3434685 | 0.78 | GABRA5 (0.52) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL4754544 | 0.76 | GABRA5 (0.50) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL5456064 | 0.76 | — | — | |
| SCHEMBL5456066 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| CN-1934100-A | Substituted quinazoline or pyridopyrimidine derivatives | BANYU PHARMA CO LTD (JP) | 2007-03-21 | — | — | CN | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |