Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 4/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRE | P78334 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630580 | 0.76 | GABRA5 (0.54) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL4756899 | 0.76 | NOS2 (0.39) | TSHRNOS2CYP2D6KMT2ACHRNB2 | |
| SCHEMBL4757326 | 0.75 | GABRP (0.43) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL19815905 | 0.73 | TSHR (0.64) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL3949668 | 0.71 | GABRA1 (0.54) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL4629632 | 0.71 | GABRA1 (0.54) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL749120 | 0.70 | — | — | |
| SCHEMBL3947564 | 0.70 | GABRA5 (0.52) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL27628213 | 0.70 | GABRP (0.42) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL3774341 | 0.69 | TSHR (0.65) | GABRA5GABRA1GABRB2TSHRGABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133344-A2 | PIPERIDINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-06 | — | — | WO | claimed |
| WO-2008133344-A2 | PIPERIDINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-06 | — | — | WO | disclosed |