Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3449358 | 1.00 | HTR2C (0.36) | HTR2CHTR6RAD52 | |
| SCHEMBL3450910 | 0.98 | HTR2C (0.37) | HTR2CHTR6 | |
| SCHEMBL1241644 | 0.83 | RIPK1 (0.31) | — | |
| SCHEMBL508981 | 0.72 | HTR2C (0.39) | HTR2CHTR6RAD52 | |
| SCHEMBL19673865 | 0.72 | HTR2C (0.39) | HTR2CHTR6RAD52 | |
| SCHEMBL3594154 | 0.70 | — | — | |
| SCHEMBL10325516 | 0.70 | HTR6 (0.46) | HTR2CHTR6 | |
| SCHEMBL28752486 | 0.70 | HTR6 (0.38) | HTR2CHTR6 | |
| SCHEMBL3448296 | 0.70 | SLC6A1 (0.36) | HTR6 | |
| SCHEMBL2383924 | 0.69 | KDM4E (0.37) | HTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |