Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 11/20 | 0.42 |
| ▸ | TACR1 | P25103 | 9/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7750300 | 0.99 | CCR2 (0.41) | CCR2TACR1CCR5DRD2TACR2 | |
| SCHEMBL7765750 | 0.83 | CCR5 (0.55) | TACR1CCR5TACR2 | |
| SCHEMBL4631612 | 0.82 | TACR1 (0.42) | CCR2TACR1CCR5TACR2 | |
| SCHEMBL4630713 | 0.81 | TACR1 (0.39) | TACR1TACR2 | |
| Hydrochloric Acid SCHEMBL7749222 | 0.81 | TACR1 (0.41) | CCR2TACR1CCR5TACR2 | |
| SCHEMBL22901986 | 0.81 | TACR1 (0.63) | TACR1CCR5TACR2 | |
| Hydrochloric Acid SCHEMBL8483405 | 0.81 | CCR5 (0.54) | TACR1CCR5TACR2 | |
| Hydrochloric Acid SCHEMBL8840258 | 0.81 | CCR5 (0.54) | TACR1CCR5TACR2 | |
| SCHEMBL8991959 | 0.81 | TACR1 (0.63) | TACR1CCR5TACR2 | |
| SCHEMBL4631735 | 0.81 | TACR1 (0.47) | TACR1CCR5TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1923391-A1 | Substituted heterocyclic compounds, method for preparing same and pharmaceutical compositions containing them. | sanofi-aventis (FR) | 2008-05-21 | — | — | EP | disclosed |
| EP-1688416-A1 | Substituted heterocyclic compounds, their process of preparation and pharmaceutical compositions containing them | Sanofi-Aventis (FR) | 2006-08-09 | — | — | EP | disclosed |
| EP-1340754-A1 | Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SANOFI-SYNTHELABO (FR) | 2003-09-03 | — | — | EP | disclosed |
| EP-1156049-A1 | Substituted heterocyclic compounds, their process of preparation and pharmaceutical compositions containing them | SANOFI-SYNTHELABO (FR) | 2001-11-21 | — | — | EP | disclosed |
| WO-1996023787-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI (FR) | 1996-08-08 | — | — | WO | disclosed |