SCHEMBL4630835

SCHEMBL4630835

CN(C)c1ccc(C(O)/C=C/c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.59
MAPT P10636 3/20 0.50
KMT2A Q03164 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
CASP3 P42574 1/20 0.50
CYP1B1 Q16678 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
APP P05067 6/20 0.44
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 2/20 0.44
MAT2A P31153 1/20 0.42
KCNH2 Q12809 1/20 0.42
HSD17B3 P37058 1/20 0.42
MMP13 P45452 1/20 0.42
MEN1 O00255 2/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4630837 1.00 RELA (0.59) RELAMAPTKMT2ASMN1; SMN2NPC1
SCHEMBL4632463 0.93 RELA (0.59) RELAMAPTKMT2ASMN1; SMN2NPC1
SCHEMBL4632461 0.93 RELA (0.59) RELAMAPTKMT2ASMN1; SMN2NPC1
SCHEMBL19148965 0.85 ALDH1A1 (0.54) RELAMAPTKMT2ASMN1; SMN2NPC1
SCHEMBL11289362 0.83 RELA (0.63) RELAMAPTKMT2ASMN1; SMN2NPC1
SCHEMBL3892740 0.83 RELA (0.63) RELAMAPTKMT2ASMN1; SMN2NPC1
SCHEMBL477645 0.82 CYP1A2 (0.57) MAPTSMN1; SMN2ALDH1A1CYP1A2LMNA
SCHEMBL477469 0.82 CYP1A2 (0.57) MAPTSMN1; SMN2ALDH1A1CYP1A2LMNA
SCHEMBL477467 0.82 CYP1A2 (0.57) MAPTSMN1; SMN2ALDH1A1CYP1A2LMNA
SCHEMBL477646 0.82 CYP1A2 (0.57) MAPTSMN1; SMN2ALDH1A1CYP1A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1927889-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2014-06-25 EP disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
EP-1091253-B1 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO LTD (JP) 2005-03-30 EP disclosed
US-6558873-B1 Interlayer containing a compound capable of forming a complex with aluminum and a photopolymerizable photosensitive layer containing a photopolymerization initiator, an addition polymerizable compound capable of complexing with aluminum FUJI PHOTO FILM CO., LTD. (JP) 2003-05-06 US disclosed
EP-1091253-A2 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-4687727-A Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1987-08-18 US disclosed
US-4511645-A ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US disclosed
EP-0104863-A2 Light-sensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1984-04-04 EP disclosed