Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865770 | 1.00 | HTR6 (0.39) | HTR6NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL3146259 | 0.94 | CA1 (0.45) | NPC1RAB9ASMN1; SMN2CCR6PTGS1 | |
| SCHEMBL6865388 | 0.94 | CA1 (0.45) | NPC1RAB9ASMN1; SMN2CCR6PTGS1 | |
| Hydrochloric Acid SCHEMBL3120247 | 0.92 | CA1 (0.43) | NPC1RAB9ASMN1; SMN2CCR6KMT2A | |
| SCHEMBL4631229 | 0.92 | KMT2A (0.47) | NPC1RAB9ASMN1; SMN2CCR6PTGS1 | |
| Hydrochloric Acid SCHEMBL28863686 | 0.92 | CA1 (0.43) | NPC1RAB9ASMN1; SMN2CCR6KMT2A | |
| SCHEMBL14228794 | 0.92 | KMT2A (0.47) | NPC1RAB9ASMN1; SMN2CCR6PTGS1 | |
| SCHEMBL4631860 | 0.92 | KMT2A (0.47) | NPC1RAB9ASMN1; SMN2CCR6PTGS1 | |
| SCHEMBL13899831 | 0.86 | — | — | |
| SCHEMBL13948191 | 0.80 | CA1 (0.41) | NPC1LMNARAB9ASMN1; SMN2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11209421-B2 | Cytidine deaminase expression level in cancer as a new therapeutic target | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-12-28 | — | — | US | disclosed |
| US-20190293629-A1 | CYTIDINE DEAMINASE EXPRESSION LEVEL IN CANCER AS A NEW THERAPEUTIC TARGET | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-09-26 | — | — | US | disclosed |
| US-8791288-B2 | Acid-labile ester monomer having spirocyclic structure, polymer, resist composition, and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-07-29 | — | — | US | disclosed |
| US-8791288-B2 | Acid-labile ester monomer having spirocyclic structure, polymer, resist composition, and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-07-29 | — | — | US | disclosed |
| CN-101168530-B | 1,4-dioxoquinoxaline formaldehyde dihydrazone with weed control activity and its preparation method and application | UNIV HUAZHONG AGRICULTURAL | 2011-02-09 | — | — | CN | disclosed |
| US-20100304295-A1 | ACID-LABILE ESTER MONOMER HAVING SPIROCYCLIC STRUCTURE, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-02 | — | — | US | disclosed |
| US-20100304295-A1 | ACID-LABILE ESTER MONOMER HAVING SPIROCYCLIC STRUCTURE, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-02 | — | — | US | disclosed |
| EP-1768948-B1 | SUBSTITUTED AMINO COMPOUNDS AS 5-HT/NA UPTAKE INHIBITORS | GRUENENTHAL GMBH (DE) | 2008-05-21 | — | — | EP | disclosed |
| CN-101168530-A | 1,4-dioxoquinoxaline formaldehyde dihydrazone with weed control activity and its preparation method and application | UNIV HUAZHONG AGRICULTURAL (CN) | 2008-04-30 | — | — | CN | disclosed |
| US-7342133-B2 | Substituted amino compounds as 5-HT/NA uptake inhibitors | GRUENENTHAL GMBH (DE) | 2008-03-11 | — | — | US | disclosed |
| EP-1069106-A2 | Dimethyl-(3-aryl-but-3-enyl) amine derivatives with analgesic activity | Grünenthal GmbH (DE) | 2001-01-17 | — | — | EP | disclosed |
| EP-0983994-A2 | Pharmaceutically-active dimethyl-(3-aryl-but-3-enyl)-amine compounds | Grünenthal GmbH (DE) | 2000-03-08 | — | — | EP | disclosed |
| US-5811582-A | ANALGESICS | GRUENENTHAL GMBH (DE) | 1998-09-22 | — | — | US | disclosed |
| CN-1163884-A | Dimethyl-(3-aryl-but-3-enyl)-amine compounds as pharmaceutical active ingredients | GRUENENTHAL GMBH (DE) | 1997-11-05 | — | — | CN | disclosed |
| EP-0799819-A1 | Dimethyl-(3-aryl-but-3-enyl) amine derivatives with analgesic activity | Grünenthal GmbH (DE) | 1997-10-08 | — | — | EP | disclosed |
| EP-0077536-B1 | 2'-SUBSTITUTED-SPIRO(BENZOFURAN-2(3H),1'-CYCLOALKANES), A PROCESS FOR PREPARING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-07-16 | — | — | EP | disclosed |
| US-4594435-A | ANTIDEPRESSANTS; ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1986-06-10 | — | — | US | disclosed |
| US-4517311-A | 2'-Substituted-spiro[benzofuran-2(3H),1'-cycloalkanes] and their analgesic and anti-depressant compositions | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0077536-A2 | 2'-Substituted-spiro(benzofuran-2(3H),1'-cycloalkanes), a process for preparing same, pharmaceutical compositions containing such compounds and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1983-04-27 | — | — | EP | disclosed |
| US-4011226-A | ANTIULCER | JOHN WYETH & BROTHER LIMITED (EN) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100304295-A1 | ACID-LABILE ESTER MONOMER HAVING SPIROCYCLIC STRUCTURE, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS | COASY, DHCR24, HCAR1 | HTR6 4338/4885NPC1 2327/4885LMNA 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.