SCHEMBL463159

SCHEMBL463159

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nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4655335 0.93 TSHR (0.38) TSHRTDP1
SCHEMBL11590426 0.82 TSHR (0.30) TSHRTDP1
SCHEMBL6293924 0.81 TSHR (0.36) TSHRTDP1
SCHEMBL8583585 0.73 TSHR (0.33) TSHRTDP1
SCHEMBL1986410 0.69
SCHEMBL4682302 0.69 CYP2D6 (0.32)
SCHEMBL11309012 0.67
SCHEMBL12902998 0.67
SCHEMBL270702 0.67
SCHEMBL72671 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230390277-A1 METHODS TO SENSITIZE TUMORS TO TREATMENT BY IMMUNOTHERAPY OHIO STATE INNOVATION FOUNDATION 2023-12-07 US disclosed
EP-2754638-B1 FILM-FORMING MATERIAL, GROUP IV METAL OXIDE FILM AND VINYLENE DIAMIDE COMPLEX TOSOH CORP (JP) 2018-11-07 EP disclosed
CN-105001254-B The manufacturing method of film material, IV family metal oxide films 东曹株式会社 2018-09-11 CN disclosed
EP-2939996-B1 GROUP 5 METAL OXO-ALKOXO COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR MANUFACTURING GROUP 5 METAL OXIDE FILM TOSOH CORP (JP) 2018-03-21 EP disclosed
US-9663541-B2 Group 5 metal oxo-alkoxo complex, method for producing same, and method for manufacturing group 5 metal oxide film TOSOH CORPORATION (JP) 2017-05-30 US disclosed
CN-104884417-B Group 5 metal oxo-alkoxycomplex, method for producing same, and method for producing group 5 metal oxide film 东曹株式会社 2017-03-15 CN disclosed
US-9521847-B2 Synergistic weed control from applications of pyridine carboxylic acid herbicides and synthetic auxin herbicides and/or auxin transport inhibitors DOW AGROSCIENCES LLC (US) 2016-12-20 US disclosed
US-9371452-B2 Film-forming material, group IV metal oxide film and vinylenediamide complex TOSOH CORPORATION (JP) 2016-06-21 US disclosed
US-20160135458-A1 SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF PYRIDINE CARBOXYLIC ACID HERBICIDES AND SYNTHETIC AUXIN HERBICIDES AND/OR AUXIN TRANSPORT INHIBITORS DOW AGROSCIENCES 2016-05-19 US disclosed
EP-3008037-A1 HYDROXY-ETHYLENE DERIVATIVES FOR THE TREATMENT OF ARTHROSIS Merck Patent GmbH (DE) 2016-04-20 EP disclosed
EP-2058295-A1 IMIDE COMPLEX, METHOD FOR PRODUCING THE SAME, METAL-CONTAINING THIN FILM AND METHOD FOR PRODUCING THE SAME Tosoh Corporation (JP) 2009-05-13 EP disclosed
EP-1716127-A2 GUANIDINE COMPOUNDS, AND USE THEREOF AS BINDING PARTNERS FOR 5-HT5 RECEPTORS Abbott GmbH & Co. KG (DE) 2006-11-02 EP disclosed
WO-2005118545-A1 GAS-PHASE OXIDATION OF ALKYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2005-12-15 WO disclosed
WO-2005082871-A2 GUANIDINE COMPOUNDS, AND USE THEREOF AS BINDING PARTNERS FOR 5-HT5 RECEPTORS ABBOTT GMBH & CO. KG (DE) 2005-09-09 WO disclosed
EP-1549667-A1 TUMOR TARGETING AGENTS AND USES THEREOF Karyon OY (FI) 2005-07-06 EP disclosed
US-6875865-B1 Selected derivatives of K-252a CEPHALON, INC. (US) 2005-04-05 US disclosed
WO-2004031221-A9 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-07-08 WO disclosed
WO-2004031218-A1 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-04-15 WO disclosed
WO-2004031220-A1 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-04-15 WO disclosed
US-5969182-A REACTING CALCIUM CYANAMIDE WITH AN ALCOHOL, REACTING THE RESULTING SUBSTITUTED ISOUREA WITH A PRIMARY OR SECONDARY AMINE BASF AKTIENGESELLSCHAFT (DE) 1999-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160135458-A1 SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF PYRIDINE CARBOXYLIC ACID HERBICIDES AND SYNTHETIC AUXIN HERBICIDES AND/OR AUXIN TRANSPORT INHIBITORS SLC6A19, SLC16A3, SLC1A5 TSHR 907/4885TDP1 4018/4885
US-20230390277-A1 METHODS TO SENSITIZE TUMORS TO TREATMENT BY IMMUNOTHERAPY TXNRD2, PCK2, DLD TSHR 4276/4885TDP1 1464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.