SCHEMBL4631622

SCHEMBL4631622

Cc1ccc(C(=CCO)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
LMNA P02545 2/20 0.46
POLB P06746 1/20 0.46
PTGS2 P35354 1/20 0.45
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
TBXAS1 P24557 1/20 0.43
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP1B1 Q16678 1/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
CHRNA4 P43681 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4631618 1.00 NPC1 (0.50) NPC1RAB9AMEN1KMT2ACES2
SCHEMBL6419890 0.92 ALDH1A1 (0.43) NPC1RAB9AMEN1KMT2ACES2
SCHEMBL6438461 0.91 SMN1; SMN2 (0.42) NPC1RAB9AMEN1KMT2ACES2
SCHEMBL6438467 0.91 SMN1; SMN2 (0.42) NPC1RAB9AMEN1KMT2ACES2
SCHEMBL6438458 0.91 SMN1; SMN2 (0.42) NPC1RAB9AMEN1KMT2ACES2
SCHEMBL4630812 0.87 MTNR1A (0.48) MTNR1AMTNR1BTBXAS1ALDH1A1CHRNB2
SCHEMBL1744469 0.82 ALDH1A1 (0.36) MEN1KMT2ACES2CES1LMNA
SCHEMBL1744472 0.82 ALDH1A1 (0.36) MEN1KMT2ACES2CES1LMNA
SCHEMBL27622858 0.82 NPC1 (0.48) NPC1RAB9AMEN1KMT2ACES2
SCHEMBL8689513 0.82 NPC1 (0.48) NPC1RAB9AMEN1KMT2ACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1927889-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2014-06-25 EP disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
US-6972294-B1 Compounds, their preparation and use NOVO NORDISK, A/S (DK) 2005-12-06 US disclosed
EP-1091253-B1 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO LTD (JP) 2005-03-30 EP disclosed
US-6558873-B1 Interlayer containing a compound capable of forming a complex with aluminum and a photopolymerizable photosensitive layer containing a photopolymerization initiator, an addition polymerizable compound capable of complexing with aluminum FUJI PHOTO FILM CO., LTD. (JP) 2003-05-06 US disclosed
EP-1171414-A1 COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2002-01-16 EP disclosed
EP-1091253-A2 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
WO-2000063153-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-10-26 WO disclosed
US-4687727-A Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1987-08-18 US disclosed
US-4511645-A ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US disclosed
EP-0104863-A2 Light-sensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1984-04-04 EP disclosed