Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 14/20 | 0.43 |
| ▸ | PDE4A | P27815 | 6/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632439 | 0.82 | PDE4D (0.42) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL4601033 | 0.79 | EGFR (0.44) | PDE4BPDE4APDE4CPDE4DEGFR | |
| SCHEMBL816455 | 0.76 | PARP15 (0.50) | PARP15PARP10THRBPARP2 | |
| SCHEMBL12796997 | 0.76 | THRB (0.54) | EGFRTHRB | |
| SCHEMBL3216053 | 0.75 | HDAC8 (0.47) | PDE4BPDE4APDE4CPDE4DPARP15 | |
| SCHEMBL3216064 | 0.75 | HDAC8 (0.47) | PDE4BPDE4APDE4CPDE4DPARP15 | |
| SCHEMBL4600070 | 0.74 | EGFR (0.42) | PDE4BPDE4APDE4CPDE4DPARP15 | |
| SCHEMBL4602988 | 0.74 | FFAR1 (0.53) | PDE4BPDE4APDE4CPDE4DPARP15 | |
| SCHEMBL19564418 | 0.73 | THRB (0.46) | EGFRTHRB | |
| SCHEMBL4602334 | 0.72 | EGFR (0.37) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |