SCHEMBL4632092

SCHEMBL4632092

[O-][S+](c1ccccc1)c1cccc(Cl)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.35
LMNA P02545 2/20 0.35
PNMT P11086 2/20 0.33
ERCC5 P28715 1/20 0.33
FEN1 P39748 1/20 0.33
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32
CYP2A6 P11509 3/20 0.31
CYP1A2 P05177 3/20 0.31
MCOLN3 Q8TDD5 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
NFKB1 P19838 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9316516 0.87 TSHR (0.41) TSHRLMNAPNMTERCC5FEN1
SCHEMBL6908412 0.85 TSHR (0.42) TSHRLMNAPNMTERCC5FEN1
SCHEMBL4121571 0.76 TSHR (0.40) TSHRLMNAPNMTERCC5FEN1
SCHEMBL9417294 0.74 CYP3A4 (0.37) TSHRMEN1KMT2ACYP3A4
SCHEMBL5085586 0.73 TSHR (0.50) TSHRLMNAPNMTIDO1CYP2A6
SCHEMBL23568725 0.72 PNMT (0.41) TSHRLMNAPNMTIDO1CYP2A6
SCHEMBL23569271 0.72 PNMT (0.41) TSHRLMNAPNMTIDO1CYP2A6
SCHEMBL15340796 0.72 TSHR (0.39) TSHRLMNAPNMTERCC5FEN1
SCHEMBL9808986 0.72 CYP3A4 (0.42) TSHRLMNAMAPTCYP3A4NFKB1
SCHEMBL11226028 0.71 TP53 (0.38) TSHRERCC5FEN1IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3953323-A1 PROCESS FOR WORKING UP A COMPOSITION COMPRISING SOLID 4,4'-DICHLORODIPHENYL SULFOXIDE AND A SOLVENT BASF SE (DE) 2022-02-16 EP claimed
EP-3921301-A1 PROCESS FOR PRODUCING 4,4'-DICHLORODIPHENYL SULFOXIDE BASF SE (DE) 2021-12-15 EP claimed
EP-3921302-A1 PROCESS FOR PURIFYING 4,4'-DICHLORODIPHENYL SULFOXIDE BASF SE (DE) 2021-12-15 EP claimed
EP-3921303-A1 A PROCESS FOR OBTAINING 4,4'-DICHLORODIPHENYL SULFOXIDE BASF SE (DE) 2021-12-15 EP claimed
EP-3914584-A1 (C)CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFONE CRYSTALS (C) BASF SE (DE) 2021-12-01 EP claimed
EP-3820841-A1 PROCESS FOR PRODUCING 4,4'-DICHLORODIPHENYL SULFONE BASF SE (DE) 2021-05-19 EP claimed
WO-2021037675-A1 PROCESS FOR PRODUCING 4,4'-DICHLORODIPHENYL SULFONE BASF SE (DE) 2021-03-04 WO claimed
WO-2021037797-A1 (C)CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFONE CRYSTALS (C) BASF SE (DE) 2021-03-04 WO claimed
EP-3774726-A1 PROCESS FOR PRODUCING 4,4`-DICHLORODIPHENYL SULFOXIDE BASF SE (DE) 2021-02-17 EP claimed
WO-2020207929-A1 PROCESS FOR WORKING UP A COMPOSITION COMPRISING SOLID 4,4'-DICHLORODIPHENYL SULFOXIDE AND A SOLVENT BASF SE (DE) 2020-10-15 WO claimed
US-5350833-A Reaction of alkali metal sulfide and dihaloaromatic compound in amide solvent and water TOSOH CORPORATION (JP) 1994-09-27 US claimed
EP-0272903-B1 PROCESS FOR PRODUCING A POLYARYLENE SULFIDE Tosoh Corporation (JP) 1993-07-21 EP claimed
EP-0275687-B1 PROCESS FOR PREPARING POLYARYLENE SULFIDES Tosoh Corporation (JP) 1992-04-22 EP claimed
EP-0480685-A2 Process for production of polyarylene sulfides Tosoh Corporation (JP) 1992-04-15 EP claimed
US-4868275-A POLYTHIOETHERS TOSOH CORPORATION (JP) 1989-09-19 US claimed
US-4845190-A Process for preparing polyarylene sulfides with recovery of carboxylic acid TOSOH CORPORATION (JP) 1989-07-04 US claimed
EP-0320142-A2 Preparation of poly (arylene sulfide) Tosoh Corporation (JP) 1989-06-14 EP claimed
EP-0304303-A2 Preparation of poly (arylene sulfide) Tosoh Corporation (JP) 1989-02-22 EP claimed
EP-0275687-A2 Process for preparing polyarylene sulfides Tosoh Corporation (JP) 1988-07-27 EP claimed
EP-0272903-A2 Process for producing a polyarylene sulfide Tosoh Corporation (JP) 1988-06-29 EP claimed