SCHEMBL4121571

SCHEMBL4121571

O[S+](c1ccccc1)c1cccc(Cl)c1Cl

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
LMNA P02545 3/20 0.35
MAPT P10636 2/20 0.35
ALDH1A1 P00352 3/20 0.33
PNMT P11086 1/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
FEN1 P39748 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ERCC5 P28715 1/20 0.33
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32
AKR1B1 P15121 1/20 0.31
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4632092 0.76 TSHR (0.35) TSHRMEN1KMT2ALMNAMAPT
SCHEMBL2222737 0.69 TSHR (0.45) TSHRLMNAALDH1A1PNMTIDO1
SCHEMBL3201226 0.69 TSHR (0.45) TSHRLMNAALDH1A1PNMTIDO1
SCHEMBL31005101 0.69 TSHR (0.45) TSHRLMNAALDH1A1PNMTIDO1
SCHEMBL31005119 0.69 TSHR (0.45) TSHRLMNAALDH1A1PNMTIDO1
SCHEMBL6908412 0.67 TSHR (0.42) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL9316516 0.66 TSHR (0.41) TSHRLMNAALDH1A1PNMTFEN1
Phenol SCHEMBL22443298 0.64 CA12 (0.58) TSHRMEN1KMT2ALMNAMAPT
1,2-Dichlorobenzene SCHEMBL7650008 0.64 TSHR (0.71) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL23569271 0.64 PNMT (0.41) TSHRLMNAALDH1A1PNMTIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420295-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2013-04-16 US disclosed
EP-2112555-A2 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2009-10-28 EP disclosed
US-20090246690-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed