SCHEMBL6908412

SCHEMBL6908412

[O-][S+](c1cccc(Cl)c1Cl)c1cccc(Cl)c1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
PNMT P11086 2/20 0.39
CYP1A2 P05177 3/20 0.38
CYP2A6 P11509 2/20 0.38
LMNA P02545 2/20 0.36
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
NFKB1 P19838 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
IDO1 P14902 2/20 0.34
ALDH1A1 P00352 2/20 0.34
GLA P06280 1/20 0.34
ERCC5 P28715 1/20 0.33
FEN1 P39748 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
DRD2 P14416 2/20 0.31
DRD3 P35462 2/20 0.31
ADRB1 P08588 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4632092 0.85 TSHR (0.35) TSHRPNMTCYP1A2CYP2A6LMNA
SCHEMBL5085586 0.81 TSHR (0.50) TSHRPNMTCYP1A2CYP2A6LMNA
SCHEMBL23568725 0.81 PNMT (0.41) TSHRPNMTCYP1A2CYP2A6LMNA
SCHEMBL15340796 0.81 TSHR (0.39) TSHRPNMTCYP1A2CYP2A6LMNA
SCHEMBL23569271 0.81 PNMT (0.41) TSHRPNMTCYP1A2CYP2A6LMNA
SCHEMBL10408606 0.77 CYP3A4 (0.40) CYP2A6CYP3A4TDP1
SCHEMBL7112350 0.76 CYP2A6 (0.35) TSHRCYP1A2CYP2A6ALDH1A1TDP1
SCHEMBL7112346 0.76 ALDH1A1 (0.46) TSHRCYP1A2CYP2A6LMNACYP3A4
SCHEMBL28248101 0.76 TAAR1 (0.32) TAAR1
SCHEMBL23239 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108948611-A A method of eliminating polytetrafluoroethylmicroporous microporous membrane layering 宁波登越新材料科技有限公司 2018-12-07 CN claimed
WO-2024146005-A1 ISOBUTYLENE POLYMERIZATION INITIATION SYSTEM COMPOSITION, POLYMERIZATION METHOD AND USE 浙江信汇新材料股份有限公司 2024-07-11 WO disclosed
CN-116162188-B Isobutene polymerization initiation system composition, polymerization method and application 浙江信汇新材料股份有限公司 2024-01-26 CN disclosed
CN-116162188-A Isobutene polymerization initiation system composition, polymerization method and application 浙江信汇新材料股份有限公司 2023-05-26 CN disclosed
CN-115725010-A Preparation method of polyisobutylene with medium and high molecular weights, initiation system and application thereof 浙江信汇新材料股份有限公司 2023-03-03 CN disclosed
CN-109068651-A Antiparasitic isoxazoline compounds, long-acting injectable formulations containing them, methods and uses thereof 梅里亚股份有限公司 2018-12-21 CN disclosed
CN-108948611-A A method of eliminating polytetrafluoroethylmicroporous microporous membrane layering 宁波登越新材料科技有限公司 2018-12-07 CN disclosed
CN-106946751-B A method of preparing diaryl sulfide 浙江师范大学 2018-11-06 CN disclosed
CN-104419007-B Biomass polysaccharides/polyisobutene graft copolymer and preparation method thereof 北京化工大学 2017-10-31 CN disclosed
CN-106946751-A A kind of method for preparing diaryl sulfide 浙江师范大学 2017-07-14 CN disclosed
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
EP-0753540-B1 Polycarbonate resin composition MITSUBISHI ENG PLASTICS CORP (JP) 2003-06-11 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed
EP-0514835-A1 Elastomers and products having reduced hysteresis properties BRIDGESTONE CORPORATION (JP) 1992-11-25 EP disclosed