Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949463 | 0.84 | CYP2C9 (0.42) | MAPTSMN1; SMN2 | |
| SCHEMBL4952926 | 0.82 | OR51E2 (0.30) | — | |
| SCHEMBL4955458 | 0.81 | HDAC3 (0.40) | MAPTSMN1; SMN2 | |
| SCHEMBL4632774 | 0.80 | KDM4E (0.36) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4953043 | 0.78 | MAPT (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetamide SCHEMBL27629993 | 0.75 | CAD (0.39) | ALOX15 | |
| SCHEMBL4954094 | 0.73 | ACE (0.33) | KDM4EACEMMECPA1ACE2 | |
| SCHEMBL4954486 | 0.73 | TP53 (0.37) | KDM4EACEMMECPA1ACE2 | |
| SCHEMBL3394612 | 0.73 | — | — | |
| SCHEMBL4951653 | 0.72 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1584615-B1 | Use of dimercaptoamides for permanently deforming of keratinic fibres | OREAL (FR) | 2008-05-28 | — | — | EP | claimed |