Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 4/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.36 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12749574 | 0.82 | PYCR1 (0.52) | PYCR1HRH3TAAR1 | |
| SCHEMBL1009789 | 0.81 | PYCR1 (0.41) | PYCR1CARM1PRMT6PRMT8HRH3 | |
| SCHEMBL21962259 | 0.81 | PYCR1 (0.53) | PYCR1KDM4EALDH1A1MAOBTAAR1 | |
| SCHEMBL1472497 | 0.81 | NR1I2 (0.42) | PYCR1HRH3KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23032284 | 0.80 | ALDH1A1 (0.52) | PYCR1CARM1PRMT6PRMT8KDM4E | |
| Hydrochloric Acid SCHEMBL1472490 | 0.79 | PYCR1 (0.40) | PYCR1HRH3KDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25237515 | 0.78 | ALDH1A1 (0.52) | PYCR1CARM1PRMT6PRMT8KDM4E | |
| SCHEMBL22013587 | 0.78 | CA2 (0.50) | KDM4ESMN1; SMN2 | |
| SCHEMBL1009445 | 0.77 | PYCR1 (0.38) | PYCR1CARM1PRMT6PRMT8HRH3 | |
| SCHEMBL17540309 | 0.77 | PYCR1 (0.41) | PYCR1HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924561-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | Eli Lilly & Company (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007028083-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |