SCHEMBL4632483

SCHEMBL4632483

COc1ccc(C(O)C=Cc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.59
ALDH1A1 P00352 4/20 0.51
MAPT P10636 4/20 0.51
CYP3A4 P08684 3/20 0.51
CYP2C9 P11712 1/20 0.51
ALOX15 P16050 1/20 0.51
CYP2C19 P33261 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HSPD1 P10809 1/20 0.50
TNFRSF1A P19438 1/20 0.50
MAOB P27338 1/20 0.50
HSPE1 P61604 1/20 0.50
CYP1B1 Q16678 1/20 0.50
EGFR P00533 1/20 0.47
MMP1 P03956 1/20 0.47
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47
RELA Q04206 5/20 0.46
NFE2L2 Q16236 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4632481 1.00 TRPA1 (0.59) TRPA1ALDH1A1MAPTCYP3A4CYP2C9
SCHEMBL4631951 0.93 TRPA1 (0.59) TRPA1ALDH1A1MAPTCYP3A4CYP2C9
SCHEMBL4631947 0.93 TRPA1 (0.59) TRPA1ALDH1A1MAPTCYP3A4CYP2C9
SCHEMBL14839505 0.91 ALDH1A1 (0.60) TRPA1ALDH1A1MAPTCYP3A4CYP2C9
SCHEMBL16468552 0.90 TRPA1 (0.51) TRPA1ALDH1A1MAPTCYP3A4CYP2C9
SCHEMBL14839484 0.85 ALDH1A1 (0.54) TRPA1ALDH1A1MAPTCYP3A4CYP2C9
SCHEMBL14839479 0.85 ALDH1A1 (0.54) TRPA1ALDH1A1MAPTCYP3A4CYP2C9
SCHEMBL477645 0.82 CYP1A2 (0.57) TRPA1ALDH1A1MAPTCYP3A4CYP2C9
SCHEMBL477469 0.82 CYP1A2 (0.57) TRPA1ALDH1A1MAPTCYP3A4CYP2C9
SCHEMBL477467 0.82 CYP1A2 (0.57) TRPA1ALDH1A1MAPTCYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1927889-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2014-06-25 EP disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
EP-1091253-B1 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO LTD (JP) 2005-03-30 EP disclosed
US-6558873-B1 Interlayer containing a compound capable of forming a complex with aluminum and a photopolymerizable photosensitive layer containing a photopolymerization initiator, an addition polymerizable compound capable of complexing with aluminum FUJI PHOTO FILM CO., LTD. (JP) 2003-05-06 US disclosed
EP-1091253-A2 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-4687727-A Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1987-08-18 US disclosed
US-4511645-A ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US disclosed
EP-0104863-A2 Light-sensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1984-04-04 EP disclosed