Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14839479 | 1.00 | ALDH1A1 (0.54) | ALDH1A1CYP3A4MAPTCYP2C9ALOX15 | |
| SCHEMBL14839505 | 0.93 | ALDH1A1 (0.60) | ALDH1A1CYP3A4MAPTCYP2C9ALOX15 | |
| SCHEMBL14839478 | 0.88 | KDM4E (0.53) | ALDH1A1CYP3A4MAPTCYP2C9ALOX15 | |
| SCHEMBL4632481 | 0.85 | TRPA1 (0.59) | ALDH1A1CYP3A4MAPTCYP2C9ALOX15 | |
| SCHEMBL4631951 | 0.85 | TRPA1 (0.59) | ALDH1A1CYP3A4MAPTCYP2C9ALOX15 | |
| SCHEMBL4632483 | 0.85 | TRPA1 (0.59) | ALDH1A1CYP3A4MAPTCYP2C9ALOX15 | |
| SCHEMBL4631947 | 0.85 | TRPA1 (0.59) | ALDH1A1CYP3A4MAPTCYP2C9ALOX15 | |
| SCHEMBL18608170 | 0.84 | RELA (0.61) | ALDH1A1CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL9448707 | 0.83 | SLC2A1 (0.57) | ALDH1A1CYP3A4MAPTCYP2C9ALOX15 | |
| SCHEMBL9448705 | 0.83 | SLC2A1 (0.57) | ALDH1A1CYP3A4MAPTCYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2775996-B1 | USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-02-28 | — | — | EP | disclosed |
| US-20150051295-A1 | USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2015-02-19 | — | — | US | disclosed |
| US-20150051295-A1 | USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2015-02-19 | — | — | US | disclosed |
| WO-2013045098-A2 | USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2013-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051295-A1 | USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS | GPX4, EBP, CAT | ALDH1A1 134/4885CYP3A4 233/4885MAPT 1598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.