Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK4 | Q13043 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16498534 | 0.82 | HSD17B10 (0.39) | STK4PDE5AALDH1A1TSHRHSD17B10 | |
| SCHEMBL25462583 | 0.75 | STK4 (0.51) | STK4PDE5AALDH1A1TSHRTUBB4A | |
| SCHEMBL23416642 | 0.73 | GAA (0.35) | ALDH1A1TSHRHSD17B10POLBMAPT | |
| SCHEMBL25975819 | 0.72 | TRIM24 (0.35) | HSD17B10USP2POLBMAPTSMN1; SMN2 | |
| SCHEMBL15823778 | 0.71 | SMN1; SMN2 (0.42) | STK4ALDH1A1TSHRPOLBMAPT | |
| SCHEMBL7601862 | 0.71 | CYP11B2 (0.38) | HSD17B10USP2POLBMAPTSMN1; SMN2 | |
| SCHEMBL8629038 | 0.69 | CYP11B2 (0.36) | PDE5ATRIM24CYP11B1CYP11B2 | |
| SCHEMBL46331 | 0.69 | PDE3B (0.43) | TSHRPDE3BPDE3ACYP11B1CYP11B2 | |
| SCHEMBL25463701 | 0.69 | STK4 (0.52) | STK4ALDH1A1TSHRPRKDCRPS6KA3 | |
| SCHEMBL17813461 | 0.69 | BRPF1 (0.42) | HSD17B10USP2POLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151436-A2 | NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151434-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |