Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5693333 | 0.86 | GAA (0.36) | GAACYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL27875239 | 0.84 | GAA (0.31) | GAA | |
| SCHEMBL7960550 | 0.71 | TSHR (0.36) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL1269117 | 0.69 | GAA (0.34) | GAACYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL152487 | 0.68 | ALDH1A1 (0.31) | — | |
| SCHEMBL28186949 | 0.68 | TSHR (0.41) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL2189860 | 0.66 | ALDH1A1 (0.48) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL1406216 | 0.66 | HMGCR (0.42) | GAACYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL28491647 | 0.66 | TSHR (0.35) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL1919940 | 0.66 | ALDH1A1 (0.36) | GAACYP2D6TSHRCYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924261-A1 | STABLE SOLID FORMULATION OF SERTINDOLE | H.Lundbeck A/S (DK) | 2008-05-28 | — | — | EP | claimed |
| US-20070212412-A1 | STABLE SOLID FORMULATION OF SERTINDOLE | H. LUNDBECK A/S (DK) | 2007-09-13 | — | — | US | claimed |
| WO-2007065448-A1 | STABLE SOLID FORMULATION OF SERTINDOLE | H. LUNDBECK A/S (DK) | 2007-06-14 | — | — | WO | claimed |
| EP-1924261-A1 | STABLE SOLID FORMULATION OF SERTINDOLE | H.Lundbeck A/S (DK) | 2008-05-28 | — | — | EP | disclosed |
| US-20070212412-A1 | STABLE SOLID FORMULATION OF SERTINDOLE | H. LUNDBECK A/S (DK) | 2007-09-13 | — | — | US | disclosed |
| WO-2007065448-A1 | STABLE SOLID FORMULATION OF SERTINDOLE | H. LUNDBECK A/S (DK) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070212412-A1 | STABLE SOLID FORMULATION OF SERTINDOLE | TPH2, TPH1, SLC6A4 | GAA 3318/4885CYP2D6 295/4885TSHR 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.