Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602508 | 0.67 | PDE4A (0.40) | GAABCHEACHELMNA | |
| SCHEMBL26698283 | 0.66 | LMNA (0.46) | POLBGAANPSR1LMNA | |
| SCHEMBL24596803 | 0.66 | KDM4E (0.52) | POLBGAACYP1A2NPSR1LMNA | |
| SCHEMBL11556984 | 0.65 | ALDH1A1 (0.55) | GAAACHENPSR1LMNA | |
| SCHEMBL2974587 | 0.63 | MAPT (0.56) | RAB9AGAACYP1A2CYP2C19NPSR1 | |
| SCHEMBL31360836 | 0.60 | L3MBTL1 (0.66) | RAB9APOLBGAACYP1A2CYP2C19 | |
| SCHEMBL24615167 | 0.60 | L3MBTL1 (0.66) | RAB9APOLBGAACYP1A2CYP2C19 | |
| SCHEMBL9270489 | 0.60 | L3MBTL1 (0.43) | GAANPSR1LMNA | |
| SCHEMBL385973 | 0.59 | HSP90AA1 (0.59) | GAACYP1A2CYP2C19NPSR1LMNA | |
| SCHEMBL9694999 | 0.59 | MAPT (0.44) | GAANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |