Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634190 | 0.86 | SLC22A12 (0.34) | RAB9ANPC1ALDH1A1GAAHPGD | |
| SCHEMBL4632998 | 0.85 | KDM4E (0.35) | RAB9ANPC1KDM4EPABPC1ALDH1A1 | |
| SCHEMBL4633218 | 0.80 | KDM4E (0.33) | KDM4EPABPC1ALDH1A1GAAHPGD | |
| SCHEMBL4634183 | 0.78 | KDM4E (0.35) | RAB9ANPC1KDM4EPABPC1ALDH1A1 | |
| SCHEMBL5901208 | 0.73 | CYP3A4 (0.60) | SMN1; SMN2RAB9ANPC1ALOX15KDM4E | |
| SCHEMBL4664696 | 0.73 | CA12 (0.51) | SMN1; SMN2RAB9ANPC1ALOX15PABPC1 | |
| SCHEMBL4634178 | 0.72 | CA12 (0.43) | SMN1; SMN2RAB9ANPC1ALOX15KDM4E | |
| SCHEMBL5901696 | 0.71 | CYP3A4 (0.53) | SMN1; SMN2RAB9ANPC1ALOX15KDM4E | |
| SCHEMBL5901336 | 0.69 | PPIA (0.47) | SMN1; SMN2RAB9ANPC1ALOX15PDE2A | |
| SCHEMBL4632328 | 0.69 | KMT2A (0.49) | SMN1; SMN2RAB9ANPC1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926714-A1 | ISOTOPICALLY SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | Nycomed GmbH (DE) | 2008-06-04 | — | — | EP | claimed |
| WO-2007023135-A1 | ISOTOPICALLY SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2007-03-01 | — | — | WO | claimed |
| EP-1926714-A1 | ISOTOPICALLY SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | Nycomed GmbH (DE) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007023135-A1 | ISOTOPICALLY SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2007-03-01 | — | — | WO | disclosed |